BACKGROUND Coronary artery bypass graft surgery (CABG) compared with percutaneous coronary intervention (PCI) reduces mortality in patients with diabetes mellitus. However, prior trials compared CABG with balloon angioplasty or older generation stents, and it is not known if the gap between CABG and PCI can be reduced by newer generation drug-eluting stents. METHODS AND RESULTS PUBMED/EMBASE/...

BACKGROUND Left main coronary artery (LMCA) bifurcation and heavily calcified lesions are common and challenging to treat percutaneously. Rotational atherectomy (RA) may be beneficial in this setting to facilitate stent placement though direct supporting evidence is lacking. This study sought to analyze patients who underwent RA of the LMCA. METHODS Consecutive cases involving RA of the LMCA ...

BACKGROUND We investigated the incidences, predictors, and clinical outcomes of acute and late stent malapposition detected by optical coherence tomography (OCT) after drug-eluting stent implantation. METHODS AND RESULTS We analyzed the OCT images from 351 patients with 356 lesions who received poststent and follow-up OCT examinations. Acute stent malapposition was observed in 62% of lesions....

Over the past decade, drug-eluting stents (DES) have greatly transformed the field of interventional cardiology. Generally, three components are included in a DES system: a metal stent platform, a drug carrier or so called ‘stent coating’ and a drug. As such, stent coating plays an important role in the performance of DES. This article will review the evolution of stent coatings and their role ...

Abstract Background Although several clinical reports demonstrated a durable patency rate after novel fluoropolymer-coated paclitaxel-eluting stent (Eluvia; Boston Scientific, Marlborough, MA, USA) placement, aneurysmal degeneration drug-eluting (Eluvia) placement has raised concerns. Here, we report case with progressive aneurysm formation on serial angiography and intravascular ultrasound ove...

Background: This study was conducted to analyze the influences of stent surface area (SSA), platelet distribution width (PDW), and joint effect these 2 risk factors on major adverse cardiovascular events (MACEs) in patients treated with percutaneous coronary intervention (PCI) together drug-eluting (DES) implantation.

Stent fracture is an emerging complication of coronary stenting. Stent fractures were originally reported in the superficial femoral arteries but have since been reported in almost all vascular sites. They are the result of the complex interplay among stent design, the stented segment, plaque morphology, deployment technique, including forceful exaggerated motion in the atrioventricular groove ...

BACKGROUND The long-term safety and efficacy of drug-eluting coronary stents have been questioned. METHODS We evaluated 47,967 patients in Sweden who received a coronary stent and were entered into the Swedish Coronary Angiography and Angioplasty Registry between 2003 and 2006 and for whom complete follow-up data were available for 1 to 5 years (mean, 2.7). In the primary analysis, we compare...

INTRODUCTION This work reports on the development of a biodegradable dual-drug-eluting stent with sequential-like and sustainable drug-release of anti-platelet acetylsalicylic acid and anti-smooth muscle cell (SMC) proliferative paclitaxel. METHODS To fabricate the biodegradable stents, poly-L-lactide strips are first cut from a solvent-casted film. They are rolled onto the surface of a metal...