A simplified microbiological assay for determining the folate content of red cells is described. As in previously reported methods Lactobacillus casei is used as test organism but two modifications are introduced. First, haemolysis is carried out in water containing 1 g.% of ascorbic acid; secondly, haemolysates are not incubated before the assay. Using this assay, recovery of pteroylglutamic a...

objective(s): incidence of neurocognitive and psychological disorders may be related to serum homocystein (hcy), cobalamin (vitamin b12 ) and folate levels in old people. the aim of this study was to assess the relation between hcy, cobalamin, folate and neurocognitive and/or psychological disorders in the elderly.   materials and methods: in this cross-sectional study, 280 subjects with ≥ 65 y...

In this note, the concepts of (G1,G2)-open, (G1,G2)-closed, (G1,G2)-quotient and (G1,G2)-perfect mappings on arbitrary sets are introduced some theorems them established firstly. particular, results improve corresponding in [17]. Secondly, we give a partial answer to question posed by L. Liu [14]. Finally, properties G-topological groups, G-connectedness totally G-disconnectedness groups discus...

STUDY OBJECTIVE To investigate the effect of the voluntary folate fortification policy in Australia on serum folate and total plasma homocysteine (tHcy) concentrations. DESIGN Population based cohort study. SETTING Perth, Western Australia. PARTICIPANTS Men and women aged 27 to 77 years (n = 468), who were originally randomly selected from the Perth electoral roll. The cohort was surveyed...

POSTER 1CATEGORY:DATABASES IN EPIDEMIOLOGICAL STUDIES FOLATE FORTIFICATION OF BREAD AND GRAINS: INTAKE OF THE ELDERLY IS AFFECTED BY FOOD SOURCES OF FOLATE. K.M. Koehler, S.L. Pareo-Tubbeh, L.J. Romero, R.N. Baumgartner, P.J. Garry, Univ. of New Mexico School of Medicine, Albuquerque, NM. Folate fortification of breads & grains will be implemented to prevent neural tube birth defects. This coul...

Lactobacillus salivarius cells contain an inducible transport system for folate. Influx via this system is time- and temperature-dependent, requires glucose and glutamine for optimum activity, and is half-maximal at folate concentrations in the nanomolar range. The folate internalized after 30 min at 30 degrees C is not released from the cells by excess extracellular folate and is recovered in ...

PURPOSE National data on folate status are missing in Sweden, and regional data indicate folate insufficiency in up to more than 25% of the study populations. The objectives were to determine folate intake and status in the adult Swedish population as well as identifying dietary patterns associated with beneficial folate status. METHODS Folate intake was estimated using a web-based 4-d food r...

Folate-protein conjugates can be nondestructively delivered into a cell's cytoplasm via folate receptor-mediated endocytosis if (i) the target cells express a folate-binding protein, and (ii) if the folate is linked to its attached protein at a site that does not interfere with receptor recognition. Because such conjugates have been observed to remain in endosomal compartments for extended peri...

Folate is an important nutrient for cell growth and division in all organisms. Many microorganisms including prokaryotes and eukaryotes can synthesize their own folate while humans cannot. To assimilate folate into the cell a folate transporter is required for uptake through the cell membrane. Three types of folate transporters are known to exist in humans to facilitate the uptake of folate: Re...