OBJECTIVE To assess the preventive effect of a cyclooxygenase 2 inhibitor, celecoxib (Celebrex; G.D. Searle & Co, Skokie, Ill), in UV-induced skin cancer in hairless mice. DESIGN Randomized dose-response study. A total of 75 SKH-HR-1 female hairless mice, aged 2 months, were randomized into control, low-dose (200 mg twice daily human dose equivalent), and high-dose (400 mg twice daily human d...

[1] The Nowcast of Atmospheric Ionizing Radiation for Aviation Safety (NAIRAS) is a real-time, global, physics-based model used to assess radiation exposure to commercial aircrews and passengers. The model is a free-running physics-based model in the sense that there are no adjustment factors applied to nudge the model into agreement with measurements. The model predicts dosimetric quantities i...

A(t) = Activity at Time t Bq = Becquerel Ci = Curie CLP = Contract Laboratory Program D = Absorbed Dose DCF = Dose Conversion Factor Per Unit Intake H = Effective Dose Equivalent E H = Dose Equivalent Averaged Over Tissue or T Organ T H = Committed Effective Dose Equivalent Per E,50 Unit Intake H = Committed Dose Equivalent Averaged Over T,50 Tissue T LET = Linear Energy Transfer LLD = Lower Li...

objective: radiation effects induced in non-irradiated cells are termed radiation-induced bystander effects (ribe). the present study intends to examine the ribe response of qu-db bystander cells to first, second and third radiation fractions and compare their cumulative outcome with an equal, single acute dose. materials and methods: this experimental study irradiated three groups of target ce...

– gafchromic xrct radiochromic film is a self developing high sensitivity radiochromic filmproduct which can be used for assessment of delivered radiation doses which could match applications suchas computed tomography (ct) dosimetry. the dose response of gafchromic xrct radiochromic film hasbeen measured with reflectance spectrophotometry and desktop scanners. the film automatically changescol...