We investigated the forces that connect the genetic program of development to morphogenesis in Drosophila. We focused on dorsal closure, a powerful model system for development and wound healing. We found that the bulk of progress toward closure is driven by contractility in supracellular "purse strings" and in the amnioserosa, whereas adhesion-mediated zipping coordinates the forces produced b...

In Drosophila, dorsal-ventral polarity is determined by a maternally encoded signal transduction pathway that culminates in the graded nuclear localization of the Rel protein, Dorsal. Dorsal is retained in the cytoplasm by the IkappaB protein, Cactus. Signal-dependent phosphorylation of Cactus results in the degradation of Cactus and the nuclear targeting of Dorsal. We present an in-depth study...

Acute experimental allergic neuritis was induced in Lewis rats by inoculation with bovine intradural root myelin and adjuvants. In terminal experiments, sensory conduction was assessed in rats with hindlimb ataxia and weakness by stimulating the exposed sciatic nerve and recording directly from the exposed L-4 spinal nerve, dorsal root ganglion, dorsal root, and dorsal root entry zone. Focal co...

The intracellular part of the Rel signal transduction pathway in Drosophila is encoded by Toll, tube, pelle, dorsal, and cactus, and it functions to form the dorsal-ventral axis in the Drosophila embryo. Upon activation of the transmembrane receptor Toll, Dorsal dissociates from its cytoplasmic inhibitor Cactus and enters the nucleus. Tube and Pelle are required to relay the signal from Toll to...

...............................................................................208

Considerable evidence suggests that there is functional heterogeneity in the control of behavior by the dorsal striatum. Dorsomedial striatum may support goal-directed behavior by representing associations between responses and outcomes (R-O associations). The dorsolateral striatum, in contrast, may support motor habits by encoding associations between stimuli and responses (S-R associations). ...

Nandus banshlaii, sp. nov. described from the Banshlai River of West Bengal. This species is distinguished all its congeners in having a golden brown body live and combination characters like longest head snout length (44.28% SL 35.58% HL respectively) two Indian containing largest eye diameter (22.22% HL), pre-dorsal (47.16% SL), shortest pectoral fin (14.60% SL) smallest dorsal base (45.53% S...

100 cases of extradural spinal compression comprising 74% of all cases of spinal  compression were included. ver-tebral and extravertebral compression occurred with  equal frequency.  1. most of tjhe cases occurred between 20-50 years of age, with no significant dif'fe'rerlce1s between various causes, except in vertebral hemangioma which tend o affect the younger age groups (10-20). males were ...

OBJECTIVE To compare both the dorsal onlay technique of Barbagli and the dorsal inlay technique of Asopa for the management of long anterior urethral stricture. METHODS From January 2010 to May 2012, a total of 47 patients with long anterior urethral strictures were randomized into two groups. The first group included 25 patients who were managed by dorsal onlay buccal mucosal graft urethropl...