Domino reactions, which enable formations of several chemical bonds and multi-step transformation in one-pot process, have received much attention as an efficient synthetic methodology to preserve chemists from time-consuming purification protocols and protection-deprotection procedures. Furthermore, the domino processes containing skeletal rearrangement have been utilized for constructions of ...

We have analyzed the Drosophila immune response in domino mutant larvae, which are devoid of blood cells. The domino mutants have a good larval viability, but they die as prepupae. We show that, on immune challenge, induction of the genes encoding antimicrobial peptides in the fat body is not affected significantly in the mutant larvae, indicating that hemocytes are not essential in this proces...

PPh3-Catalyzed aza-MBH domino reaction of salicyl N-tosylimines with γ-CH3 substituted allenoates is reported. Readily available imines and allenoates are converted to benzoxazepine derivatives in one step. Wherein, functionalization of C-H bonds of γ-substituted allenoate has been developed in this domino process.

background : to the best of the authors’ knowledge, to date, no systematic study has been carried out in tabriz city to investigate the extent, frequency, causes, and major outcome(s) of falling accidents in the houses of rural and urban areas of this city. the current study was, therefore, undertaken to address some of these issues. methods: in this cross-sectional retrospective study, 43170 i...

In this paper, we continue the study of domino-tilings of Aztec diamonds (introduced in [1] and [2]). In particular, we look at certain ways of placing “barriers” in the Aztec diamond, with the constraint that no domino may cross a barrier. Remarkably, the number of constrained tilings is independent of the placement of the barriers. We do not know of a simple combinatorial explanation of this ...

We describe here a Tf₂NH-catalyzed formal (3+3) cycloaddition of silyl enol ethers with acrylates as a new domino reaction. In the domino sequence, the catalyst activates Michael addition, deprotonation of the resulting silyloxonium cation and intramolecular Claisen condensation. It was found that reaction modes significantly depend on the reaction temperature. We also examined the mechanistic ...

In this paper, we propose four wide domino circuits to improve the robustness and reduce the power consumption. All proposed circuits use small potential at the source of the pull down network in the standby mode. Simulation is done using 90nm HSPICE for 32 input OR gate. Our proposed circuits reduce power consumption by 11.75% to 41.85%, improvement of unity noise gain by 41.03% to 90.87% and ...