many physicians have received a frantic call from anxious parents stating that their child had stopped breathing, become limp, or turned blue but then had recovered quickly. an apparent life-threatening event (alte) is defined as “an episode that is frightening to the observer, and is characterized by some combination of apnea, color change, marked change in muscle tone, choking, gagging, or co...

sudden cardiac death (scd) in a young athlete is rare, but catastrophic. exercise acts as a risk factor for scd in people with cardiovascular disease. a diversity of cardiovascular disorders including hypertrophic cardiomyopathy, congenital coronary anomalies, arrhythmogenic right ventricular dysplasia, dilated cardiomyopathy, aortic rupture due to marfan syndrome, myocarditis, valvular disease...

This issue of Methods contains a series of articles that cover the major techniques used to measure apoptosis, necrosis and variations thereof, at the population, single cell, organelle and molecular level. Although we used to think of apoptosis as programmed or regulated cell death and necrosis as strictly non-programmed or unregulated cell death [1,2], data have emerged in recent years which ...