INTRODUCTION Mycosis fungoides (MF) is the most common form of primary cutaneous T cell lymphoma. Narrowband ultraviolet B light (NBUVB) is used increasingly in treating MF because of its good toleration and well-established management. CONCERNS To discuss the risk factors and underlying pathogenic factors in the patients with secondary skin diseases after NBUVB therapy. METHODS We report i...

Porokeratosis is an inherited, clonal disorder of epidermal keratinization classically characterized by development of single or multiple annular lesions with raised, sharply marginated, keratotic ridge and central atrophy. This clinical presentation may vary with different types of porokeratosis but histopathologically unified by the consistent finding of ‘cornoid lamella’. Porokeratosis may d...

Porokeratosis represents a spectrum of clinical diseases. Multiple variants have been described including porokeratosis ptychotropica, a rare subtype. The coexistence of two or more variants of porokeratosis in a single patient is regarded as a rare occurrence. Here we report a patient with porokeratosis ptychotropica with coexistent porokeratosis of Mibelli. The patient was a 47-year-old man w...

Porokeratosis is the common name of several diseases of unknown pathogenesis, which are similar in clinical appearance. It was first described in 1893 and was thought to be a disorder of sweat glands, hence the name porokeratosis. The lesion that can be found in all cases is annular, with atrophic center, and hyperkeratotic outer ring. Cases of porokeratosis have been linked with genetic herita...

In patients who develop early signs of fotocarcinogenesi, the actinic keratosis are one of the most frequent events that can lead to problems of therapeutic management, especially if for business reasons or lifestyle, they are repeatedly and chronically exposed to the sun. In these patients the lesions are often widespread and recurrent, and may require repeated treatment cycles. It is in these...

Linear porokeratosis is a genodermatosis, caused by a clonal proliferation of keratinocytes along the lines of Blaschko. This type of porokeratosis is particularly susceptible to malignant degeneration e.g. to Bowen disease, a squamous cell carcinoma (SCC) in situ with the potential for significant lateral spread. Here we report a case of linear porokeratosis on the left leg of a 56-year-old ma...

Linear porokeratosis is one of the infrequent variants of porokeratosis, a rare disorder of keratinization that may develop into several epidermal malignancies, among them squamous cell carcinoma. Clinical surveillance for malignancy is imperative, but in cases when large or many lesions are present, surgical removal of porokeratosis lesions would result in an unfavorable amount of scarring. A ...

Porokeratosis is a disorder of keratinisation whose pathogenesis is yet unclear. It has been postulated that it results from the proliferation of an abnormal clone of keratinocytes, triggered by several factors, such as immunosuppression or prolonged ultraviolet exposure. Various clinical forms are recognized whose common denominator is a keratotic ring surrounding a central zone of atrophy. Th...

There is evidence from randomized controlled trials (RCTs) that PDT is an effective treatment for selected patients with actinic keratoses of the scalp compared with placebo or cryotherapy. The evidence to date suggests that PDT is less effective than surgery and radiotherapy and of similar efficacy to cryotherapy for treating low-risk basal cell carcinoma (BCC) (e.g., superficial and nodular)....