In this study, a novel mesoporous silica nanoparticles drug carrier contributes to improving the solubility, dissolution, and the oral bioavailability of apigenin (AP). The apigenin of solid dispersion of mesoporous silica nanoparticles (AP-MSN) was prepared by physical absorption method and also, in-vitro drug release and in-vivo bioavailability performance were evaluated. Based on its solubil...

Background: Alcohol dependence (AD) is a major reason for morbidity and visits to emergency medical settings. However, the detection of AD is often difficult or overlooked. This study aimed to develop a brief screening questionnaire in Hindi language for detection of AD in an emergency medical setting. Methods:  The authors in consultation devised a set of questions related to AD in the Hindi l...

Objective(s) Alzheimer’s disease (AD) is a complex disease with multifactorial etiology. Inflammation has been proven to have an important role in the pathogenesis of AD. Both CCR2 and CCR5 genes expression increase in AD patients comparing to control subjects. CCR5 gene encodes a protein which is a member of the beta chemokine receptors family of integral membrane proteins. CCR5-Δ32 is a gene...

This article presents the approach and current findings of the EO2HEAVEN project, in particular from the Saxony Case Study. The aim of the Case Study is the conceptual design of a Spatial Information Infrastructure for better understanding the complex relationship between ambient air quality and its influence on the human health. This includes air quality modelling and a statistical analysis of...

This manuscript presents an overview of the current experimental situation regarding nucleon decay and the measured flux of atmospheric neutrinos. Previous and on-going experiments are reviewed, the data are presented, and new outstanding questions are posed. The SuperKamiokande project is described and its expected sensitivity for improving measurements of the nucleon lifetime and the atmosphe...

Let Ng(d) be the set of primes p such that the order of g modulo p, ordp(g), is divisible by a prescribed integer d. Wiertelak showed that this set has a natural density, δg(d), with δg(d) ∈ Q>0. Let Ng(d)(x) be the number of primes p ≤ x that are in Ng(d). A simple identity for Ng(d)(x) is established. It is used to derive a more compact expression for δg(d) than known hitherto.

Applications of Lagrangian dispersion modeling to the analysis of changes in the specific absorption of elemental carbon J. C. Doran, J. D. Fast, J. C. Barnard, A. Laskin, Y. Desyaterik, M. K. Gilles, and R. J. Hopkins Pacific Northwest National Laboratory, P.O. Box 999, Richland, Washington, USA Lawrence Berkeley National Laboratory, Berkeley, CA, USA Received: 25 September 2007 – Accepted: 10...

The successful launch of the Landsat 8 satellite with two thermal infrared bands on February 11, 2013, for continuous Earth observation provided another opportunity for remote sensing of land surface temperature (LST). However, calibration notices issued by the United States Geological Survey (USGS) indicated that data from the Landsat 8 Thermal Infrared Sensor (TIRS) Band 11 have large uncerta...