Mimics of discontinuous epitopes of for example bacterial or viral proteins may have considerable potential for the development of synthetic vaccines, especially if conserved epitopes can be mimicked. However, due to the structural complexity and size of discontinuous epitopes molecular construction of these mimics remains challeging. We present here a convergent route for the assembly of disco...

Tacit knowledge attenuates particularly quickly in organizations that experience discontinuous membership: the coming and going of organizational roles or positions during a workflow process. Because knowledge flows enable workflows, and workflows drive performance, theory suggests that dynamic knowledge—particularly tacit knowledge—is critical for competitive advantage. This research seeks to ...

AbstrAct Tacit knowledge attenuates particularly quickly in organizations that experience discontinuous membership: the coming and going of organizational roles or positions during a workflow process. Since knowledge flows enable workflows, and workflows drive performance, theory suggests that dynamic knowledge—particularly tacit knowledge—is critical for competitive advantage. This research se...

In this paper, we propose and numerically investigate a family of locally divergence-free central discontinuous Galerkin methods for ideal magnetohydrodynamic (MHD) equations. The methods are based on the original central discontinuous Galerkin methods (SIAM Journal on Numerical Analysis 45 (2007) 2442-2467) for hyperbolic equations, with the use of approximating functions that are exactly dive...

Splenogonadal fusion is a rare entity with approximately 150 reported cases until the year 2005. The entity is a rare congenital anomaly in which there is fusion of splenic and gonadal anlagen or mesonephric derivatives. Splenogonadal fusion has two continuous and discontinuous types. About ten cases have been reported to be associated with bilateral cryptorchidism in literature. Very few cases...

Early-age hydration with neutral or alkaline (0 M to 8 M) solutions was studied in calcium sulfoaluminate clinker (CSA) using isothermal conduction calorimetry, X-ray diffraction (both continuous and discontinuous, i.e., after detaining isopropanol) infrared spectroscopy. Hydration 0.1 NaOH observed be similar water. At the next highest concentration (1 M), however, reaction rate slower, due pr...

We study single-phase flow in a fractured porous medium at macroscopic scale that allows us to model fractures individually. The is governed by Darcy’s law both and matrix. derive new mixed-dimensional model, where are represented -dimensional interfaces between subdomains for . In particular, we suggest generalization of the [V. Martin, J. Jaffré, E. Roberts, SIAM Sci. Comput., 26 (2005), pp. ...

We have desiged an adaptive ENO-wavelet transform for approximating discontinuous functions without oscillations near the discontinuities. Our approach is to apply the one-side information idea from Essentially Non-Oscillatory (ENO) schemes for numerical shock capturing to standard wavelet transforms. This transform retains the essential properties and advantages of standard wavelet transforms ...

The microalgae cultivation can be used as alternative sources of food, in agriculture, residual water treatment, and biofuels production. Semicontinuous cultivation is little studied but is more cost-effective than the discontinuous (batch) cultivation. In the semicontinuous cultivation, the microalga is maintained in better concentration of nutrients and the photoinhibition by excessive cell i...