The temporomandibular joint (TMJ) disc is a little understood structure that, unfortunately, exhibits a plethora of pathologic disorders. Tissue engineering approaches may be warranted to address TMJ disc pathophysiology, but first a clear understanding of structure-function relationships needs to be developed, especially as they relate to the regenerative potential of the tissue. In this revie...

PURPOSE To determine the frequency of optic disc hemorrhages in a rural Indian population. METHODS The population-based Central Indian Eye and Medical Study included 4711 subjects. Mean age was 48.5±12.9 years (range: 30-100 years). Color optic disc photographs were examined. RESULTS Optic disc photographs were available for 4570 (97.0%) subjects. Prevalence of disc hemorrhages was 17/8869 ...

PURPOSE To evaluate whether optic disc hemorrhages are associated with faster rates of estimated retinal ganglion cell (RGC) loss in glaucoma. METHODS A longitudinal observational cohort study of 222 eyes of 122 patients with glaucoma recruited from the Diagnostic Innovations Glaucoma Study (DIGS) followed for an average of 3.74±0.85 years. All subjects had optical coherence tomography and st...

17 Recent studies have shown that chromogenic cephalosporin tests are inferior to disc zone edge tests in 18 detecting penicillinase in Staphylococcus aureus isolates resulting in a change to CLSI and EUCAST 19 guidelines in 2012. We sought to confirm these findings using Australian isolates and compare the 20 performance of the CLSI and EUCAST methods which use different disc strengths, penici...

We derive age-metallicity relations (AMRs) and orbital parameters for the 1658 solar neighbourhood stars to which accurate distances are measured by the HIPPARCOS satellite. The sample stars comprise 1382 thin disc stars, 229 thick disc stars, and 47 halo stars according to their orbital parameters. We find a considerable scatter for thin disc AMR along the one-zone Galactic chemical evolution ...

Degenerative disc disease and disc bulge in the lumbar spine are common sources of lower back pain. Little is known regarding disc bulge migration and lumbar segmental mobility as the lumbar spine moves from flexion to extension. In this study, 329 symptomatic (low back pain with or without neurological symptoms) patients with an average age of 43.5 years with varying degrees of disc degenerati...

BACKGROUND Recent reported results have added to the weight of evidence supporting association between disc degeneration and Modic changes. Endplate or Modic changes are also associated with increased body mass index. The most recent study from Teichtahl et al. titled 'Modic changes in the lumbar spine and their association with body composition, fat distribution and intervertebral disc height ...

17 Recent studies have shown that chromogenic cephalosporin tests are inferior to disc zone edge tests in 18 detecting penicillinase in Staphylococcus aureus isolates resulting in a change to CLSI and EUCAST 19 guidelines in 2012. We sought to confirm these findings using Australian isolates and compare the 20 performance of the CLSI and EUCAST methods which use different disc strengths, penici...

STUDY DESIGN A kinematic analysis of cervical intervertebral disc deformation during simulated whiplash using the whole cervical spine with muscle force replication model was performed. OBJECTIVES To quantify anulus fibrosus fiber strain, disc shear strain, and axial disc deformation in the cervical spine during simulated whiplash. SUMMARY OF BACKGROUND DATA Clinical studies have documented...

It has previously been demonstrated that disc puncture in the rat induced changes in grooming and wet dog shakes, two behavioral changes that may be linked to discomfort and neuropathic pain. In this study the aim was to separate the effects of disc injury and the epidural presence of nucleus pulposus. Following anesthesia, the L4-5 disc was exposed using a dorsal approach. Ten rats received a ...