To evaluate the effect of eucalyptus, sappan, and cinnamon leaf bark extract on percentage S. mutans biofilm formation. The test group was divided into a negative control (1% Dimethyl sulfoxide), treatment (eucalyptus, leaves at concentrations 50%, 25%, 12.5%, respectively), positive (0.2% chlorhexidine). Each concentration barks extract, Brain Heart Infusion Broth (BHI-B), bacteria according t...

Melanins are universal biopolymers, the main biological function of which is to protect living organisms from adverse factors. Interest in these dark pigments arises due prospects for their use medicine, cosmeceuticals, bioremediation, bioelectronics, and other fields. In this work, a complex scheme was developed isolate melanins lichen Leptogium furfuraceum (Harm.), symbiotic extremophilic org...

Antimicrobial peptides (AMPs) are now used instead of conventional antimicrobial substances because they do not induce resistance in microbial cells. The first goal this study was to investigate how various dissolution solvents, such as dimethyl sulfoxide (DMSO), phosphate buffered saline (PBS) and autoclaved deionized (DI) water, affect the potency an AMP (HHC-36) modified with L -propargylgly...

A capillary zone electrophoresis (CZE) method, with UV detection and in the presence of dimethyl-beta-CD, was optimized by means of an experimental design for the separation and the simultaneous quantitation of ephedrine, pseudoephedrine, norephedrine (phenylpropanolamine) and norpseudoephedrine (cathine) in urine without any extraction. In this application, the optimization of the analytical c...

The aim of this work was the development of a family of novel water soluble Zinc(II) phthalocyanines (Pc) for the photodynamic inactivation of Gram-negative bacteria. Pc derivatives 1a, 2a and 3a containing trimethylammonium groups with varied number and nature of the groups at peripheral positions were synthesized by cyclotetramerization of dimethyl amino substituted phthalonitriles in the pre...

Abstract A self-assembly Pd-Schiff base complex was synthesized and used as an electrochemical sensor in phosphate buffer solution, where it enhanced the electrocatalytic activity toward paracetamol detection. The Schiff {(HL) = (4-(((Z)-3-(hydroxyimino) butan-2-ylidene) amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one)} selected to prepare Pd-based complexes due its high antimicrobial...

Although pesticide use is widespread, little is known about potential adverse health effects of in utero exposure. We investigated the effects of organophosphate pesticide exposure during pregnancy on fetal growth and gestational duration in a cohort of low-income, Latina women living in an agricultural community in the Salinas Valley, California. We measured nonspecific metabolites of organoph...