AIMS AND BACKGROUND To report the clinical outcomes of four patients with pituitary metastases treated with radiotherapy. METHODS Retrospective chart review of four cases. RESULTS The mean age of the patients was 66 years; two were women and two were men. The mean duration of symptoms at initial presentation of the primary tumor was 2.25 months. The location of the primary tumor was the bre...

The role of radiotherapy in the treatment of hepatocellular carcinoma (HCC) has been limited to date, because the liver has a low tolerance to radiation. However, reconstructing tumors and surrounding organs via a three-dimensional conformal planning system can avoid excess radiotherapy exposure to the rest of the liver and adjacent organs. Recently, the concept of "adaptive radiotherapy," such...

PURPOSE Tomotherapy for intensity-modulated radiation has been demonstrated to reduce unnecessary irradiations to adjacent organs at risk (OARs). The purpose of this study was to compare the dosimetric parameters between Tomotherapy and three-dimensional conformal radiotherapy (3D-CRT) in rectal cancer patients. MATERIALS AND METHODS We redesigned three-dimensional conformal plans for 20 rect...

PURPOSE To prospectively assess the efficacy of the selective serotonin inhibitor escitalopram on painful bone metastases, in combination with external beam irradiation. METHODS Forty-three patients with cancer metastatic to bone and suffering from depression were treated with 3 Dimensional Conformal Radiotherapy (3DCRT) (30 Gy; 3 Gy/fraction, 5 days/week) combined with escitalopram (20 mg/da...

Recent advances have improved the effectiveness, decreased the complications, and expanded the implications of radiation therapy. These advances include three-dimensional conformal radiation therapy, intensity-modulated radiation therapy, stereotactic radiotherapy, brachytherapy, and radioimmunotherapy. Each of these modalities has improved radiation targeting, thereby limiting radiation exposu...

Due to acute and particularly chronic postirradiation complications in radiotherapy of the prostate, the dose application, and consequently also the irradiation effect, are restricted. The incidence and grade of acute and chronic complications depend upon the dose and volume of the surrounding organs involved in the irradiation area.1-4 As the restrictions on dose application should in no way b...

Introduction. In locally advanced cancers of the cervix, endometrium and vulva, radiotherapy is primary treatment modality. recent years, new modern techniques external radiation have been developed in oncology, with goal dose escalation to target volume, while sparing healthy tissues. The aim this study determine impact volumetric modulated arc therapy on clinical outcomes patients gynecologic...

Intensity modulated radiotherapy (IMRT) is a modern radiotherapy technique that was implemented in the mid-1990s. It allows closer shaping of dose, to target volumes, thereby sparing organs at risk (OARs). Before the IMRT-era, two-dimensional radiotherapy (2DRT) and later three-dimensional conformal radiotherapy (3DCRT) were the techniques of choice, but this robust way of irradiating caused mo...