Objective: Alopecia areata (AA) is a common, chronic disorder presents as patchy loss of hair on the scalp, beard area, eyebrows and other parts of body. Trichoscopy, dermoscopy of hair, is a non-invasive diagnostic tool which helps in visualization of subsurface features. Diagnosis of AA is easy, however, diffuse alopecia, alopecia on the eyebrows, patients presenting with total loss of hair c...

Rodrigues M, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-220679 Description A 15-year-old healthy adolescent girl went to her physician consultation because she was preoccupied with progressive thinning of her hair since 11 years old. In the last year, she noticed an aggravation, with an excessive hair loss. She does not have hirsutism, acne, asthenia, menstrual irregularities or weight vari...

Background: One of the key questions in biochemistry is why cell becomes aged and what are the involved factors? Why cell growth is stopped after some divisions and cells become senescent? This occurs in a greater frame in the whole body and cells dye after a while. Androgenetic alopecia (AGA) is characterized by a loss or decrease in hair follicle size, which could be related to the loss of ha...

1 Moo Yeol Hyun, MD Beom Joon Kim, MD, PhD Department of Dermatology Chung-Ang University College of Medicine Seoul, Korea Changjin Lee, MD, PhD Jae Wook Kim, MD, PhD Hugel, Inc. Gangwon-do, Korea Sir: B toxin type A (BTXA) has been in use for more than 20 years in the treatment of various neurological conditions and aesthetic treatments.1,2 BTXA is also occasionally used to treat alopecia; how...

From the Department of Dermatology and Skin Science, University of British Columbia, and Vancouver Coastal Health Research Institute — both in Vancouver, Canada; and the Department of Dermatology, New York University, New York. Address reprint requests to Dr. Shapiro at the Department of Dermatology and Skin Science, University of British Columbia, 835 W. 10th Ave., Vancouver, BC V5Z 4E8, Canada.

Aplasia cutis and other scarring alopecias Congenital absence of skin (aplasia cutis) presents on the scalp as one or more noninflammatory well defined oval or circular ulcers, crusted areas (fig 1) or as scars. Lesions usually occur over the vertex in or adjacent to the midline and may involve skin only or occasionally may extend deeply to bone and dura. Complications include secondary infecti...

objective(s): noise-induced hearing loss (nihl) is the major cause of acquired hearing loss.  celecoxib, a cyclooxygenase-2 (cox-2) inhibitor, is a non- steroidal anti- inflammatory drug (nsaid) with known antioxidant and antineoplastic activity. therefore, we monitored the extent of temporary noise- induced threshold shifts (tts) and cochlear damage caused by high level 4- khz noise exposure t...

Female androgenetic alopecia or female-pattern alopecia is one of the most common causes of hair loss, affecting 50 % of women over their lifetime. The appearance of this condition is the cause of significant stress and psychological problems, making appropriate management important. Cases exist in which it is associated with hyperandrogenism. Here, we review the different clinical forms (diffu...

The review of the literature regarding non-Hodgkin's lymphoma and occupational and environmental factors presented at this workshop suggested associations with viruses, solvents, and hair dyes. A population-based case-control study among men from Iowa and Minnesota notes similar associations. Workers engaged in metal working, hair care, painting, and dry cleaning experienced nonsignificant exce...

objective: objective: dermal papilla and hair epithelial stem cells regulate hair formation and growth cycle. damage to or losing of these cells can cause hair loss. although several studies have claimed to reconstitute hairs using rodent cells in animal model, a stable human hair follicle reconstitution protocol needs more studies. here in this study we evaluated hair induction through injecti...