Polynomials are fascinating because they have many facets to their personalities. By definition, a polynomial f ∈ C[x] is an expression of the form (1.1) f(x) = a0 + a1x+ · · ·+ anx , where the aj are complex numbers. By the fundamental theorem of algebra, f also has a representation as a product (1.2) f(x) = an(x− x1) · · · (x− xn), where xj are the roots of f . The fact that there are two way...

Monitoring of quality of care has always been an important part of health care. Self-regulation and external standards require care providers to furnish safe environments for the patient. Similarities in methods used by quality improvement (QI) projects and clinical research have created some confusion in differentiating the two practices. This article reviews the current literature and differe...

Many studies have suggested that the 3D organization of chromatin and proteins within the nucleus contributes to the regulation of gene expression. We tested multiple aspects of this nuclear organization model within a primary cell culture system. Oligodendrocyte lineage cells were examined to facilitate analysis of nuclear organization relative to a highly expressed tissue-specific gene, prote...

May/June 2015 • Volume 4, Number 3 • Wound Care Advisor Cellulitis is an acute, painful, and potentially serious spreading bacterial skin infection that affects mainly the subcutaneous and dermal layers. Usually of an acute onset, it’s marked by redness, warmth, swelling, and tenderness. Borders of the affected skin are characteristically irregular. Although cellulitis may occur in many body ar...

Earlier studies have shown that patients iting no platelet adhesiveness. It is postuwith von Wiilebrand’s disease are considlated that there may be two groups of ered to have normal platelets, but they patients within von Willebrand’s disease lack at least one plasma protein. Results and, further, that ristocetin will provide a are presented indicating that ristocetin, useful approach to study ...

Dental pulp stem cells (DPSCs) are multipotent stem cells derived from neural crest and mesenchyme and have the capacity to differentiate into multiple cell lineages. It has already been demonstrated that DPSCs differentiate into melanocyte-like cells but only when cultivated in a specific melanocyte differentiating medium. In this study we have shown, for the first time, that DPSCs are capable...

We review strategies for differentiating matrix-based computations, and derive symbolic and algorithmic update rules for differentiating expressions containing the Cholesky decomposition. We recommend new ‘blocked’ algorithms, based on differentiating the Cholesky algorithm DPOTRF in the LAPACK library, which uses ‘Level 3’ matrix-matrix operations from BLAS, and so is cache-friendly and easy t...

Propolis is a multicomponent, active, complex resinous substance collected by honeybees from a variety of plant sources. We have studied the effect of propolis on neurite outgrowth of SH-SY5Y human neuroblastoma cells induced to differentiate by all-trans-retinoic acid (RA). Propolis, at a concentration of 3 μg/mL, had no significant effect on the viability of differentiating SH-SY5Y cells. How...

Automated detection of masses on mammograms is challenged by the presence of dense breast parenchyma. The aim of this study was to investigate the feasibility of using wavelet-based feature analysis for differentiating masses, of varying sizes, from normal dense tissue on mammograms. The dataset analyzed consists of 166 regions of interest (ROIs) containing spiculated masses (60), circumscribed...

Terminal differentiation of erythroid cells results in terminal cell divisions followed by irreversible cell cycle withdrawal of hemoglobinized cells. The mechanisms leading to cell cycle withdrawal were assessed in stable transfectants of murine erythroleukemia cells, in which the activities of cyclin-dependent kinases (CDKs) and CDK inhibitors (CDKIs) could be tightly regulated during differe...