Two recent studies show that a neural globin tunes oxygen responses in the nematode Caenorhabditis elegans. Analysis of wild C. elegans strains suggests that the commonly used Bristol strain may have adapted to life in the laboratory.

In Web Services designs classical optimization techniques are not applicable. A possible solution to guarantee critical requirements is the use of an autonomic architecture, able to autoconfigure and to auto-tune. This study presents MAWeS (MetaPL/HeSSE Autonomic Web Services), a framework whose aim is to support the development of self-optimizing predictive autonomic systems for Web service ar...

This paper addresses the issue of the contribution of intonation to the meaning of an utterance, and more precisely of the conditions that should be met to propose a compositional approach to the meaning of intonational contours. After presenting different positions in the literature and specifying if and how much these proposals can be said compositional, we show that their differences can be ...

The PEP-II B-Factory achieved design performances in 2000. The tune shifts of the rings are already about twice the design numbers of 0.03. This requires constant adjustments from the operators during fills and top-offs. A tune feedback was envisioned first, but the wide, multi-peaked tune signals make it tricky even for a human to adjust the tunes correctly. Since tunes are strongly correlated...

Fixed-Field Alternating-Gradient (FFAG) accelerators span a large range of momenta and have markedly different reference orbits for each momemtum. In the non-scaling (NS) versions proposed for rapid acceleration, the orbits are geometrically dissimilar. In particular, none of the orbits within bending magnets are arcs of circles and this complicates tune calculation. One approach to NS-FFAG des...

The role of left and right temporal lobes in memory for songs (words sung to a tune) was investigated. Patients who had undergone focal cerebral excision for the relief of intractable epilepsy along with normal control subjects were tested in 2 recognition memory tasks. The goal of Experiment 1 was to examine recognition of words and of tunes when they were presented together in an unfamiliar s...

Emittance growth due to the non-linear beam-beam interaction is a major concern at all hadron colliders. The tunes (i.e. the rotation numbers of the transverse betatron oscillations) are always chosen to avoid low order resonances and the overlap of high order resonances does not create chaotic regions large enough to lead to significant amplitude growth. The dynamics are qualitatively differen...

This paper presents a comparative analysis of declarative intonation produced by standard speakers of German from Austria, Germany and Switzerland. The analysis was based on a directly comparable corpus of speech data. A perception test with phoneticians from the three countries suggested (1) that speakers from the three varieties produce different tunes on accented syllables, and (2) that ther...

Drosophila Dicer-1 produces microRNAs (miRNAs) from pre-miRNA, whereas Dicer-2 generates small interfering RNAs (siRNAs) from long dsRNA. Alternative splicing of the loquacious (loqs) mRNA generates three distinct Dicer partner proteins. To understand the function of each, we constructed flies expressing Loqs-PA, Loqs-PB, or Loqs-PD. Loqs-PD promotes both endo- and exo-siRNA production by Dicer...

Involuntary, spontaneous cognitions are common, everyday experiences that occur against a backdrop of deliberate goal-directed mentation (Christoff, Ream & Gabrieli, 2004). One such phenomenon may hold special promise for empirical investigation of this often elusive experience. Involuntary musical imagery (INMI) or ‘earworms’ are vivid, identifiable, and affect 91.7% of the population at least...