Abstract This article aims to investigate the identity of Socrates, compiler AP 14.1-64 (arithmetic problems and riddles). Leaving aside traditional, but very uncertain, identification with Socrates epigrammatist (D.L. 2.47), it is shown that chronological conjecture by Carcopino 1926 (late 1st century BC -2nd AD ) no longer holds. A wider time frame established (1st-4th centuries ), although e...

OBJECTIVE Little is known regarding the link between intimate partner violence (IPV), alcohol problems (AP), and depression in inner-city African American women. We sought to investigate whether abused inner-city African American women reporting AP endorsed more depressive symptoms compared to women reporting either AP or IPV or reporting neither. METHOD Participants for this cross-sectional ...

Editor’s key points † Continuous measurement of beat-to-beat arterial pressure (AP) during the dynamic phases of anaesthesia facilitates recognition and treatment of acute variations. † The non-invasive AP monitor NexfinTM was compared with invasive AP (IAP) measurements during induction of anaesthesia. † NexfinTM reliably and quickly detected acute changes in AP, but its accuracy was insuffici...

Current-clamp recordings were made from the primary (1°) and secondary (2°) branching points (BPs) of axons at the crayfish neuromuscular junction. Action potential (AP) firing initiated by current injected at the 2° BP showed strong adaptation or high-frequency firing at threshold current, whereas AP firing frequency at the 1° BP exhibited a gradual rise with increasing current amplitude. The ...

Manganese superoxide dismutase (Mn-SOD) is a primary antioxidant enzyme whose expression is essential for life in oxygen. Mn-SOD has tumor suppressor activity in a wide variety of tumors and transformed cell systems. Our initial observations revealed that Mn-SOD expression was inversely correlated with expression of AP-2 transcription factors in normal human fibroblasts and their SV-40 transfor...

Editor’s key points † Continuous measurement of beat-to-beat arterial pressure (AP) during the dynamic phases of anaesthesia facilitates recognition and treatment of acute variations. † The non-invasive AP monitor NexfinTM was compared with invasive AP (IAP) measurements during induction of anaesthesia. † NexfinTM reliably and quickly detected acute changes in AP, but its accuracy was insuffici...

background: acinetobacter spp., as important opportunistic pathogens, have been found to be responsible for an increas­ing number of nosocomial infections. this study was undertaken to investigate the antimicrobial susceptibility and molecular typing of iranian isolates of a. baumannii . methods: the study was conducted over a period of 19 months in three hospitals in tehran, iran. acinetobacte...

Cell types that generate unique lysosome-related organelles (LROs), such as melanosomes in melanocytes, populate nascent LROs with cargoes that are diverted from endosomes. Cargo sorting toward melanosomes correlates with binding via cytoplasmically exposed sorting signals to either heterotetrameric adaptor AP-1 or AP-3. Some cargoes bind both adaptors, but the relative contribution of each ada...

The AP-2 transcription factors are required for normal growth and morphogenesis during mammalian development. Previous in vitro studies have also indicated that the AP-2 family of proteins may be involved in the etiology of human breast cancer. The AP-2 genes are expressed in many human breast cancer cell lines, and critical AP-2-binding sites are present in both the ERBB-2 (HER2/neu) and estro...