Patients with multiple myeloma may present with several signs and symptoms, inclusive of hemorrhagic diathesis. This case emphasizes the need to suspect uncommon etiologies for common signs and to be aware of the atypical effects of paraproteinemia.

Immune thrombocytopenia and pulmonary tuberculosis presented concurrently in a 20 year old Thai man as a bleeding diathesis. Intravenous immunoglobulin rapidly corrected the thrombocytopenia. Immunofluorescence and immunoblot studies with platelets and mycobacteria showed the presence of platelet surface membrane IgG.

background crimean-congo hemorrhagic fever (cchf) was a rare disease in iran before 1999. during the last 15 years, it has been reported from different provinces of iran, mostly from southeastern iran. objectives this study aimed to evaluate the factors associated with poor outcome in children and adolescents with cchf. patients and methods we studied all files of children (age < 19 years old) ...

Haemorrhagic diathesis of the newborn is usually characterized by a physiological deficiency of prothrombin and probably also by a deficiency of proconvertin (van Creveld, Paulssen, Ens, Mey, Versteegh and Versteeg, 1954). Sometimes a third clotting-factor, pro-accelerin, is also lacking. We found a simultaneous deficiency both of prothrombin and pro-accelerin in some cases of intra-uterine mel...

In this paper we will explore the role of affect in the core deficit in autism and in the development of intelligence and social skills. We discuss how children with autistic spectrum disorders may uniquely, for biological reasons, miss a critical developmental capacity, the ability to connect affect or intent to motor planning and sequencing capacities as well as symbol formation and, therefor...

Weber-Christian disease (WCD) is an inflammatory disease of subcutaneous fat first described in 1892. Panush et al. I analysed the clinical and laboratory features of WCD, including chronic relapsing fever with subcutaneous non-sup­ purative nodules predominantly on lower extremities, arthralgia or ar­ thritis and myalgia. The laboratory features were elevated erythrocyte sedimentation rate, an...

BACKGROUND The present study sought to clarify the development of comorbid emotional distress by comparing different explanations for how youth develop anxiety and depressive symptoms. Specifically, we introduced the diathesis-anxiety approach (whether cognitive vulnerabilities interact with anxiety symptoms), and compared it to a causal model (anxiety symptoms predicting depressive symptoms), ...

A sizeable body of research has demonstrated that expressed emotion (EE) predicts clinical relapse in a number of distinct psychiatric disorders. These findings have provided the impetus for the development of interventions that attempt to reduce patients' relapse rates by modifying aspects of the family environment believed to be associated with high levels of EE. Despite the efficacy of these...

The role of rejection sensitivity as a critical diathesis moderating the link between adolescent relational stressors and depressive symptoms was examined using multi-method, multi-reporter data from a diverse community sample of 173 adolescents, followed from age 16 to 18. Relational stressors examined included emotional abuse, maternal behavior undermining adolescents' autonomy and relatednes...