Previous studies have shown that vessels from diabetics produce less prostacyclin in vitro than those from normal controls. To determine whether this decreased production is related to complications elective biopsy of a superficial forearm vein was performed on 12 insulin-dependent male diabetics, six with nil or minimal and six with proliferative retinopathy, and seven male controls. Vein segm...

Objective: To assess the degree of metabolic control and the presence of type 2 diabetes complications in diabetic immigrants. Methods: Cross-sectional case-control observational study, matched by age and sex. Cases: Hindustani diabetic immigrants (n= 116) and non-hindustani (n= 113). Controls: native diabetic patients with type 2 diabetes (n= 229). The relation male/female was 6.7, 0.8 y 2, re...

Diabetics have a prothrombotic state that includes increased platelet reactivity. This contributes to the less favorable clinical outcomes observed in diabetics experiencing acute coronary syndromes as well as stable coronary artery disease. Many diabetics are relatively resistant to or have insufficient response to several antithrombotic agents. In the setting of percutaneous coronary interven...

130 ABSTRACT: Diabetes mellitus is associated with elevated oxidative stress via increased generation of reactive oxygen species (ROS), and decline in antioxidant defences. Increased oxidative stress is thought to play a role in the development of diabetic complications. In the current study, vitamins A, C, and E, chromium, manganese and zinc levels were estimated in 54 diabetics attending the ...

The purpose of the study was to compare the mobility of selected joints of the limbs in diabetic and non-diabetics subjects. One hundred subjects comprising of 50 volunteer diabetics and 50 volunteer non-diabetics subjects participated in this study. The range of motion of the shoulder, elbow, wrist, fingers, hip and knee joins were measured using a double armed simple goniometer and recorded i...

The effect of the dopamine agonist, bromocriptine, and the dopamine antagonist, metoclopramide, on glucose tolerance was examined in maturity onset diabetics and normal subjects. After bromocriptine there was a lowered fasting blood glucose and improved glucose tolerance in the diabetics. The controls showed an initial improvement in glucose tolerance. A reduction in insulin levels and a marked...

Plasma C4 concentrations were measured in insulin dependent diabetics with and without microangiopathy and in controls. The diabetics had significantly lower C4 values than controls (p less than 0.001), and patients with insulin dependent diabetes and microangiopathy had lower values than those without this complication (p less than 0.001). There was a 7.1-fold increase in the prevalence of com...

Apple products have been shown to prevent skin, mammary gland and colon carcinogenesis in animal models. Epidemiological observations indicate that regular consumption of one or more apples a day may reduce the risk for lung and colon cancer. The present study investigated the potential effects of apples on fasting blood sugar and lipid parameters in Type II diabetics’ patients.Study includes 9...

This systematic review investigated whether the insulin sensitiser metformin has a geroprotective effect in humans. Pubmed and Embase were searched along with databases of unpublished studies. Eligible research investigated the effect of metformin on all-cause mortality or diseases of ageing relative to non-diabetic populations or diabetics receiving other therapies with adjustment for disease ...

BACKGROUND Diabetes mellitus (DM) is a metabolic disorder characterised by chronic hyperglycaemia with disturbances in carbohydrate, fat and protein metabolism arising from defect in insulin secretion or action or both. The clinical guidelines recommend measurement of BMI as "vital signs" for evaluating the obese and diabetic patients. METHODS This study was carried out on 160 diabetics, whic...