objective: phthalates, which are commonly used to render plastics into soft and flexible materials, have also been determined as developmental and reproductive toxicants in human and animals. the purpose of this study was to evaluate the effect of mono-(2- ethylhexyl) phthalate (mehp) and di-(2-ethylhexyl) phthalate (dehp) oral administrations on maturation of mouse oocytes, apoptosis and gene ...

Background/Aim. Phthalates are recognized as endocrine-disrupting compounds and extensively present in a variety of everyday products. Chronic exposure to phthalates is suspected be associated with range health disorders. The aim the study was examine abundance phthalate metabolites urine samples among adults Autonomous Province Vojvodina, Serbia, determine prevalence healthy individuals those ...

Oils extracted from plants have been used since ancient times and in many cultures .frying oils are used in many countries all around the world including Iran. Therefore it is of great importance to ensure the safety of these food products which are usually delivered in polyethylene terephthalate (PET) bottles. This study has investigated the effect of storage time and temperature on the migrat...

Bis(2-ethylhexyl) phthalate is extracted from artificial kidneys, both in vivo and in vitro. Perfusion of whole blood through arterial-,venous tubing (that supplied with the dialyzer) for 1 h in vitro yielded 3.23 mg of the compound, while similar perfusion of the tubing plus the artificial kidney yielded 6.10 mg. Its mean concentration after dialysis in patients undergoing hemodialysis was 751...

Oxidative stress has been recognized as one of the most important contributors to infertility in both males and females. Exposure to many environmental chemicals, such as phthalates, has been shown to induce oxidative stress. In a longitudinal study designed to assess exposure to environmental chemicals and fecundity in couples who were planning pregnancy, 894 urine samples were collected from ...

program prior to designing and conducting toxicology studies. The purpose of the research concept document is to outline the general elements of a research program that would address the specific public health concerns that prompted the nomination of the substance or issue for study. It may also encompass substance-specific studies that address larger public health issues or topics in toxicolog...

the brain and spinal cord have a limited capacity for self-repair under damaged conditions. one of the best options to overcome these limitations involves the use of phytochemicals as potential therapeutic agents. in this study, we have aimed to investigate the effects of di-(2-ethylhexyl) phthalate (dehp) on hippocampus-derived neural stem cells (nscs) proliferation to search phytochemical can...

The use of polyvinyl chloride gloves containing di(2-ethylhexyl) phthalate for food contact applications is restricted. In their place, polyvinyl chloride gloves containing non-phthalate plasticizers (PVC-NP) have been introduced. They contained unknown substances, so they were studied by GC/MS, HR-MS and NMR. The chemical structures of the unknown substances were confirmed to be diethylene gly...

Infants, whose growth and development are highly dependent upon the endocrine system, are particularly vulnerable to endocrine disruptor exposure. In our study, we examined whether or not alkylphenols, bisphenol A, benzophenone, di(2-ethylhexyl)adipate and 10 phthalates are present in containers of baby food. Furthermore, the migration into food-simulating solvents was also examined. Sixteen ty...