OBJECTIVE In skeletal muscle, glucocorticoids induce catabolism and proteolysis which is accomplished via the ubiquitin (Ub) proteolytic pathway. Cardiac muscle is a striated muscle which, compared to skeletal muscle, more abundantly expresses components of the Ub pathway, thus suggesting an important role for this pathway in heart physiology. The aim of our study was to explore the role of the...

Abstract Introduction Although insufficient sleep is a known risk factor for metabolic syndrome (MetS), the circadian timing of also involved in cardiac and regulation. As result, misalignment sleep-wake cycle, which highly prevalent adolescents, may independently impact burden MetS youth. Methods We analyzed data from 277 population-based randomly-selected adolescents Penn State Child Cohort (...

Results Analysis of four day food records following each testing session revealed average values of 1588 ± 116.7 kcal/day, 43.6 ± 7.3% protein, 35 ± 5.4% carbohydrates, 17.8 ± 7.98% fat throughout the testing period. Additionally, the participant lost 6.09 kg (13.4lb) and 2.5 BMI units. Furthermore both HHBIA (.935; p = .006) and JP7 (.954; p = 0.003) were significantly and positively correlate...

An increased susceptibility to disease in neonatal calves may be attributable to high glucocorticoid levels that influence immune reactions. We tested whether dexamethasone (DEXA) administration influences the proliferation, apoptosis, and number of B- and T-lymphocytes in Peyer's patches (PP) and thymus in calves fed colostrum (C) or a milk-derived formula. All calves were subcutaneously admin...

The objective of the present study was to compare anthropometry with bioelectrical impedance (BIA) in relation to densitometry (dual-energy X-ray absorptiometry; DEXA) as methods of nutritional assessment and body composition in out-patients with chronic pulmonary obstructive disease (COPD). We conducted a cross-sectional clinical study with sixty-one patients with COPD (forty-two men and ninet...

Foot-to-foot bioelectrical impedance analysis (BIA) is simple and non-invasive, making it particularly suitable for use in children. There is insufficient evidence of the validity of foot-to-foot BIA compared with dual-energy X-ray absorptiometry (DEXA) as the criterion method in healthy young children. Our objective was to assess the validity of foot-to-foot BIA against DEXA in a large cohort ...