purpose: to evaluate the underlying causes of rhegmatogenous retinal detachment (rrd) in eyes operated for this reasion. methods: out of 1473 patients who underwent retinal detachment surgery, records of 369 patients were randomly selected and evaluated for the types of retinal breaks, the underlying disorders, and location of breaks. results: fifty-two percents of patients were less than 50 ye...

Experiments conducted in high-performance 1.0-1.2 MA 6 MW NBI-heated H-mode plasmas with a high flux expansion radiative divertor in NSTX demonstrate that significant divertor peak heat flux reduction and access to detachment may be facilitated naturally in a highly-shaped spherical torus (ST) configuration. Improved plasma performance with high βp = 15− 25 %, a high bootstrap current fraction ...

In the flagellum of the African sleeping sickness parasite Trypanosoma brucei calmodulin (CaM) is found within the paraflagellar rod (PFR), an elaborate extra-axonemal structure, and the axoneme. In dissecting mechanisms of motility regulation we analysed CaM function using RNAi. Unexpectedly CaM depletion resulted in total and catastrophic failure in PFR assembly; even connections linking axon...

Geckos can run rapidly on walls and ceilings, requiring high friction forces (on walls) and adhesion forces (on ceilings), with typical step intervals of approximately 20 ms. The rapid switching between gecko foot attachment and detachment is analyzed theoretically based on a tape model that incorporates the adhesion and friction forces originating from the van der Waals forces between the subm...

Reelin binds to very low-density lipoprotein receptor and apolipoprotein E receptor 2, thereby inducing mDab1 phosphorylation and activation of the phosphatidylinositide 3 kinase (PI3K) pathway. Here we demonstrate that Reelin activates the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) pathway, which leads to the phosphorylation of Erk1/2 proteins. The inhibition ...