The relative ability of various precursors to generate functional B cells in vivo was assessed by transferring normal, chromosomally-marked CBA/H-T6T6 cells to irradiated or unirradiated immunodeficient CBA/N mice. Emergence of donor-derived B cells was monitored by means of a B-cell cloning assay (in which CBA/N cells are inactive), and by karyotpic analysis of lymphoid, myeloid, and stem cell...

A single-chain fragment variable (scFv) recognizing β2-glycoprotein 1 (β2GPI) from humans and other species was isolated from a human phage display library and engineered to contain an IgG1 hingeCH2-CH3 domain. The scFv-Fc directed against β2GPI domain I induced thrombosis and fetal loss, thus mimicking the effect of antibodies from patients with antiphospholipid syndrome (APS). Complement is i...

background: one of the first‑line assessment tools for fetal surveillance is nonstress test (nst), although it is limited by a high rate of false‑nonreactive results. this study was performed to investigate if external stimulation from vibroacoustic and halogen light could help in provoking fetal responsiveness and altering nst results. materials and methods: this is a clinical trial. sampling ...

background: opium is one of the most commonly abused opiates in developing countries including iran. considering the importance of maternal health on the newborn, we aimed to assess the effect of opium abuse on fetal heart rate (fhr) characteristics in a sample of pregnant women in zahedan, southeast iran. methods: this cross-sectional study was done on 100 pregnant women referring to ali-ibn-a...

background and aim: maternal concept is part of the feminine gender role. the important part of the maternal concept is the unique relationship experience between mother and child that begins with  maternal-fetal attachment(mfa) during pregnancy. the aim of this study is predict the mfa according to gender role in pregnant women in shiraz city. methods:this descriptive correlational study was c...

background: alcohol is a potent teratogen and alcohol use in pregnancy and the periconception period can cause many complications in mother, fetus and neonate.  discussion: alcohol in the mother's blood passes through the placenta to the baby through the umbilical cord. drinking alcohol during pregnancy can cause miscarriage, stillbirth, and a range of lifelong disorders. alcohol-related birth ...

four crossbred cows with mummified fetus were utilized for the study. the cows were subjected to gynecological examination and based on the findings the cases were diagnosed as mummified fetus. the cows were treated with 2 mg estradiol valerate and 500 µg cloprostenol and were examined every 12 hr after 24 hr of the treatment for cervical dilatation and other signs related to fetal expulsion. t...