Plants with pesticidal properties have been investigated for decades as alternatives to synthetics, but most progress has been shown in the laboratory. Consequently, research on pesticidal plants is failing to address gaps in our knowledge that constrain their uptake. Some of these gaps are their evaluation of their efficacy under field conditions, their economic viability and impact on benefic...

Angiogenesis is necessary for solid tumor growth and dissemination, thus representing a promising target not only in cancer therapy but also in prevention. The principle of cancer chemoprevention is based on the use of agents that, while devoid of collateral effects, are able to interfere with processes associated with malignant progression, including cancer related inflammation (CRI). Since ou...

The last two decades have witnessed explosive growth in the study of natural and other cancer chemopreventive agents (1, 2). Extensive preclinical data have been generated for natural agents, and many (such as green tea, curcumin, phenyl isothiocyanate, indole-3-carbinol, silibinin, lycopene, genistein, selenium, and vitamins A, E, and D) are currently in different phases of clinical testing (3...