Dideoxy fingerprinting (ddF) was used as a tool to search for a generic set of conditions with sufficient power to detect virtually all mutations. For each condition tested, a very large sample of mutation-containing, single-stranded segments (about 1500) were analyzed with ddF. Correlation coefficients identified pairs of conditions in which single-strand conformation polymorphism (SSCP) mobil...

A (v, k, λ) difference family ((v, k, λ)-DF in short) over an abelian group G of order v is a collection F = {Bi | i ∈ I} of k-subsets of G, called base blocks, such that each nonzero element of G can be represented in precisely λ ways as a difference of two elements lying in some base blocks in F . A disjoint (v, k, λ)-DF is a difference family with disjoint blocks. In this paper, it is proved...

In order to achieve the goal of "Peak Carbon Dioxide Emissions and Neutrality" as scheduled, China's service industry must green development. this paper, we use super-efficiency SBM-DDF integration model measure efficiency in 30 provinces China during 2011-2019. On basis level industry, Dagum Gini coefficient spatial Markov chain are used analyze source regional gap dynamic evolution four major...

The MIXED procedure of SAS® has made use of the linear mixed model accessible to researchers. However, a sticky problem for the procedure has been the specification of appropriate denominator degrees of freedom for test statistics for fixed effects in both balanced designs with simple covariance structures and complex designs involving complicated covariance structures, unbalanced data and/or s...

SQSTM1/p62 (sequestosome 1) selectively targets polyubiquitinated proteins for degradation via macroautophagy and the proteasome. Additionally, SQSTM1 shuttles between the cytoplasmic and nuclear compartments, although its role in the nucleus is relatively unknown. Here, we report that SQSTM1 dynamically associates with DNA damage foci (DDF) and regulates DNA repair. Upon induction of DNA damag...

Alexithymia, an impairment of affective and cognitive emotional processing, is often associated with human immunodeficiency virus (HIV) and may reflect effects of the virus on brain areas that are also important for multiple cognitive functions, such as the prefrontal and anterior cingulate cortices. We hypothesized that there would be a correlation between extent of alexithymia and cognitive p...

BACKGROUND Alexithymia, the difficulty in describing or recognizing emotions, has been associated with various psychosomatic pathologies including psoriasis. The aim of this study was to examine the prevalence of alexithymia and its association with anxiety and depression in patients with psoriasis compared with healthy participants, while taking into consideration demographic and clinical vari...

A new filter named the maximum likelihood-based iterated divided difference filter (MLIDDF) is developed to improve the low state estimation accuracy of nonlinear state estimation due to large initial estimation errors and nonlinearity of measurement equations. The MLIDDF algorithm is derivative-free and implemented only by calculating the functional evaluations. The MLIDDF algorithm involves t...

While transmitting information over multipath channels, multiple access interference cannot be easily eliminated. However, it is possible to design detectors that estimate the channel parameters accurately. The conventional detector may be unable to recover the transmitted information from the weaker users. The need for accurate parameter estimates in the presence of multiple access interferenc...

AIM Paroxysmal nocturnal haemoglobinuria (PNH) is caused by deficient biosynthesis of the glycosylphosphatidylinositol (GPI) anchor in haemopoietic stem cells. Mutation of the phosphatidylinositol glycan class A (PIG-A) gene, an X linked gene that participates in the first step of GPI anchor biosynthesis, is responsible for PNH. The characteristics of somatic mutation of the PIG-A gene in Korea...