Background: The use of dendritic cells (DCs) as a cellular adjuvant provides a promis-ing approach in immunotherapy of cancer. It has been demonstrated that Listeria mono-cytogenes activated DCs pulsed ex vivo with tumor antigens trigger a systemic Th1-biased specific immune response and a single dose of this vaccine will cause a consider-able anti tumor immunity. Objective: The present study w...

The ontology of dynamic capabilities (DCs) is grounded in a systemic perspective organisational strategy. In controversial move, DCs theory adopts systems thinking as metaphorical reference, not possible research method. Systemic methodologies can provide holistic management perception and guide managers to develop differently, considering the deliberate learning design process non-linear dynam...