background: radiation therapy is an effective method used for treatment of many types of cancers. however, this method can cause unwanted side effects such as bone marrow suppression. in this study, the effect of oral administration of biogenic selenium nanoparticles (senps) on total and differentiated white cells profile of balb/c mice exposed to x-ray radiation was investigated and compared w...

objective: carthamus tinctorius l.(c. tinctorius) is used as a food additive but also has medicinal applications. the present work was designed to investigate its probable side effects on the histology and function of the kidney in the mice. materials and methods: sixty adult balb/c mice were randomly distributed into one control and three experimental groups. the control group received only di...

objective: the beneficial effects of clove on toothache have been well documented. we have also previously shown the analgesic effects of clove essential oil. the present work was done to investigate the analgesic effects of the aqueous extract of clove using hot plate test. the possible role of opioid receptors in the analgesic effects of clove was also investigated using naloxone. materials a...

background and objectives: the magnetotactic bacterium magnetospirillum gryphiswaldense (msr-1) mineralizes the magnetite (fe3 o4) crystals and organizes a highly ordered intracellular structure, called the magnetosome. iron transport system supports the biogenesis of magnetite. although iron is an essential trace element for many metabolic pathways of the body, increase or decrease in iron wil...

objective(s) quinazolinones are heterocyclic components (able to form cyclized compounds) which have several medical effects such as anti-malarial, spasmolytic, anti-microbial, sedative, etc. they are also known for their fungicidal properties, inhibition of tyrosine-kinase and dna repair enzyme poly (adp-ribose) polymerase (parp) and are also effective in treatment of cancer, diabetes, and par...

introduction: topiramate is a newly anti-convulsant drug, which acts as nmda glutamate receptor antagonist as well as the gabab receptor agonist. it is used for physical dependence to opioids as well as cocaine, nicotine, alcohol and ecstasy dependence. in the present study attempts were made to further identification of the effects of topiramate on the acquisition and expression of morphine-in...

background: diagnostic models are frequently used to assess the role of risk factors on disease complications, and therefore to avoid them. missing data is an issue that challenges the model making. the aim of this study was to develop a diagnostic model to predict death in hiv/ aids patients when missing data exist. methods: hiv patients (n=1460) referred to voluntary consoling and testing cen...

background: regarding the prevalence of epilepsy in human society and with respect to inefficiency of the usual treatments, finding new strategies and methods for the medical treatment of epileptic patients are essential. henbane seed has been used in iranian traditional medicine as an anti-convulsion herb. with this regard the present study was carried out to consider the anti-convulsive effec...

for the first time, a spectrum of morphological abnormalities have been produced in developingmouse embryos (n=50), by injecting (ip) 75 and 100 mg/kg of maternal body weight of a new quinazolinonederivative, 4(3h)quinazolinone-2-propyl-2-phenylethyl(qppe), on days 9, 10 and 11 of gestation.measurements of the length of the crown-rump (cr), weight of body of the embryos and placenta on day 17sh...

in order to assess the immunopathological effects of aqueous echinacea purpurea extract (epe) on mice experimentally challenged with pasteurella multocida serotype a, forty female balb/c mice were randomly divided into four groups. the groups included a control group (received sterile distilled water 2 times/week for 2 weeks, intraperitoneally and then 100 μl sterile saline intranasally), a pma...