This paper describes a concept of concentration and binary separation of particles and its experimental confirmations for digital microfluidics where droplets are driven by the mechanism of electrowetting-on-dielectric (EWOD). As a fundamental separation unit, a binary separation scheme is developed, separating two different types of particles in one droplet into two droplets, one type each. Th...

introduction: the most important change in medical education is a shift from didactic teacher-centered and subject-based teaching to the use of interactive, problem-based, student-centered learning. student-centered approach is a teaching approach t that encompasses replacing lectures with active learning, integrating self-paced learning programs and cooperative group situations, ultimately hol...

Asymmetric division of progenitor/stem cells generates both self-renewing and differentiating progeny and is fundamental to development and regeneration. How this process is regulated in the vertebrate brain remains incompletely understood. Here, we use time-lapse imaging to track radial glia progenitor behavior in the developing zebrafish brain. We find that asymmetric division invariably gene...