OBJECTIVE To describe the morphologic spectrum of metastatic malignant melanoma (MM) cells involving the breast and to explore the diagnostic utility of HMB45, Mart-1, Melan-A and T311 (antityrosinase) antibodies in fine needle aspiration material of MM metastatic to the breast. STUDY DESIGN Cytologic material from 21 cases (18 women) was reviewed for cytomorphology (epithelioid, spindled, mi...

Adoptive cell transfer (ACT) of ex vivo engineered autologous lymphocytes encoding high-affinity MART-1/HLA-A 0201–specific T-cell receptor (TCR)a/b chains (F5 CTL), densely infiltrate into sites of metastatic disease, mediating dramatic but partial clinical responses in patients with melanoma. We hypothesized that MART-1 downmodulation in addition to aberrant apoptotic/survival signaling could...

Presented in this paper is a neural back propagation algorithm for reconstructing two-dimensional CT images from a small number of projection data. The paper extends the work in [1], in which a backpropagation algorithm is applied to the CT image reconstruction problem. The delta rule of the ordinary backpropagation algorithm is modified using a ‘secondary’ teaching signal and the ‘Resilient ba...

This paper explores the widely accepted view thatWal-Mart causes significant harm to the traditional, small ‘‘mom and pop’’ business sector of the U.S. economy. We present the first rigorous econometric investigation of this issue by examining the rate of self-employment and the number of small employer establishments using both time series and cross-sectional data. We also examine alternative ...

Wal-Mart has created tremendous economic benefits for consumers by providing more choices at lower prices, especially in communities that had only local retail monopolies prior to the chain‘s arrival. Yet no retailer evokes stronger negative emotions than this chain. Recent media attention has focused on questionable labor practices and other impacts of the stores, while academic studies have e...

This paper investigates the impact of store location, a retailer's most costly and long-term marketing mix decision, on retailer revenues. We estimate models of consumer spending at the leading packaged goods retailers in a metropolitan market based on two dimensions of retail location: (i) proximity to consumers, i.e., travel times, and (ii) proximity to other stores, i.e., agglomeration. Both...

The correlations among the thirteen personality scores yielded by the Guilford schedule for factors STDCR, and the Guilford-Mart in schedules for factors GAMIN, and O, Ag, and Co, as reported by Lovell, were factored by the centroid method. The purpose was to see how many factors were represented by the thirteen scores; therefore the test reliabilities were used in the diagonal cells. I t was f...

Publishing and consuming structured data on the Web is becoming more and more common across domains as varied as the public sector, the media, cultural institutions, the manufacturing industry or retailers. Kasabi, an online data market based on linked data principles, offers data publishers an easy way to publish, link and monetise data, while giving developers of data-centric applications acc...

This paper describes a method for developing dimensional models from traditional Entity Relationship models. This can be used to design data warehouses and data marts based on enterprise data models. The first step of the method involves classifying entities in the data model into a number of categories. The second step involves identifying hierarchies that exist in the model. The final step in...

Business organizations have increasingly become the target of social movement activists, but relatively little is known about the antecedents and effectiveness of these protests. We fill in the literature gap by studying American communities’ protests against Wal-Mart’s entry from 1998 to 2005. The incidence of protests is significantly related to local political ideology, community stability, ...