Defensins are antimicrobial peptides that act mainly by disrupting the structure of bacterial cell membranes and found in many compartments body. play a central role defense against pathogens they considered part innate immune response. Material methods-Reagents: Animal culture media - Growth medium D-MEM, RPMI alpha -MEM was purchased from gibco, CA, USA. Fetal bovine serum (FBS)was obtained I...

Pharmacognosy Research,2022,14,4,499-503.DOI:10.5530/pres.14.4.72Published:October 2022Type:Original ArticleAuthors:Amir Saeed, and Ahmed Alharbi Author(s) affiliations:Amir Saeed1,2, Alharbi1 1Department of Medical Laboratory Sciences, College Applied University Hail, KSA. 2Department Microbiology, Faculty Sciences Technology, Khartoum, SUDAN. Abstract:Background: Cervical cancer is widely ack...

Aims Studies have shown that probiotic bacteria inhibit the onset and progression of carcinogenesis through different pathways. Our objective in this study was to determine effect on expression growth-related genes Rel A, IKB, Casp3 HT29 colon cancer cells Methods & Materials In study, Lactobacillus brevis were first cultured, after supply media conditioning, they treated cells. The bacteri...