It is well established that soybean products contain the phytoestrogens daidzein and genistein. 1-3 We have measured the levels of these compounds in several soy-based infant formulas available in New Zealand. The quantities recommended by manufacturers for infant feeding provide an intake (per kg body weight) of approximately three to five times as much daidzein and genistein than amounts whic...


 Purpose: To determine the effect of fresh soy milk and its compounds (coumestrol, daidzein genistein) on apoptosis in human leukemic cells peripheral blood mononuclear (PBMC).
 Methods: The apoptotic (K562, Jurkat, U937) PBMC was determined by flow cytometry. from healthy donors were isolated conducting density gradient centrifugation principle. Lymphoprep cytotoxicity evaluated 3-(...

• EAEP increased extractability and bioaccessibility of soy isoflavone aglycones. phenolic compounds. resulted in extracts with higher antioxidant potential. improved the functional biological properties extracts. The effects enzymatic extraction strategies on extractability, bioconversion, biologically active aglycones, total content, activity aqueous from full-fat flour were evaluated. Protea...

Biochanin A and formononetin are methylated isoflavones, abundant in legumes, which can be converted genistein daidzein by means of an O-demethylation reaction. Our objective was to transform these isoflavones into higher biological activity bioavailability compounds, such as genistein. Prior screening, using 10 lactic acid bacteria (LAB) 3 bifidobacteria strains, revealed that only 7 lactobaci...

The formation mechanism for the potent antioxidative o-dihydroxyisoflavones, 8-hydroxydaidzein (8-OHD) and 8-hydroxygenistein (8-OHG), was studied by incubating whole soybeans in a solid culture and a soybean extract in a liquid culture with Aspergillus saitoi. Analyses of changes in the isoflavone analogue content, β-glucosidase activity, and isoflavone hydroxylation ability indicated that 8-O...

Asian populations are thought to receive significant health benefits from traditional diets rich in soybeans due to high isoflavone contents. However, available epidemiologic data only weakly support this hypothesis. The present study was carried out to assess the pharmacokinetics of isoflavones in South Korean women after ingestion of soy-based foods. Twenty-six healthy female volunteers (20-3...