The aim of this study was to compare the b- and d-waves of the ERG, evoked respectively by ON and OFF stimuli. The experiments were carried out on frogs. The d-wave is facilitated by light adaptation and relatively high stimulus intensity. The depth profiles of b- and d-waves are different. Aspartic acid abolished only the b-wave whereas nembutal affected the d-wave. These results suggested th...

Three different surface-enhanced Raman scattering (SERS) spectra are recorded for aspartic acid on H(2)O silver sols under different concentrations and pH values. The analysis of the results shows that it interacts with the metal surface in its dianionic form in two different ways, depending on the pH and concentration. Moreover, in some cases the fumarate anion is detected, which results from ...

objective(s) the central nucleus of the amygdala (cea) is a forebrain structure which is important in regulation of ingestive behavior and there is direct and circumstantial evidence to indicate that some circuits involved with feeding behavior include glutamatergic elements. the present study examined whether administration of nma (n-methyl-dl-aspartic acid) or mk801 into the cea altered water...

The employment of thermodynamics in biochemistry has been restricted, until recently, to the use of first law data. In the last few years a beginning has been made in the application of the second law; i.e., of free energy data (1, 2). The development of this field is limited by the paucity of available free energy data. We have therefore undertaken the systematic determination of the free ener...

A B6DAO-/- mouse strain lacking D-amino acid oxidase (DAO) activity with the genetic background of C57BL strain, frequently used to produce disease model mice in current medical/life science areas, was newly developed. In plasma control C57BL/6J and mutant mice, five acids widely found mammals were determined using a highly-selective two-dimensional LC-MS/MS system. As targets, D-alanine (Ala),...

No one of the methods proposed for the synthesis of aspartic acid is entirely satisfactory as a practical procedure. The synthesis, described in a recent paper (1) from this laboratory, has been utilized in preparing 50 to 60 gm. lots of recrystallized aspartic acid but even here the beginning reagents are expensive, the over-all yield is only about 30 per cent of the theoretical, and the proce...