OBJECTIVE Resin cements, regardless of their biocompatibility, have been widely used in restorative dentistry during the recent years. These cements contain hydroxy ethyl methacrylate (HEMA) molecules which are claimed to penetrate into dentinal tubules and may affect dental pulp. Since tooth preparation for metal ceramic restorations involves a large surface of the tooth, cytotoxicity of these...

The aim of this study was to evaluate the cytotoxicity induced by orthodontic bands through survival tests on Saccharomyces cerevisiae, a microorganism that presents several genetic and biochemical characteristics similar to human cells. Three groups of bands were evaluated: silver soldered (SSB), laser soldered (LSB), and bands without any solder (WSB). Yeast cells were directly exposed to the...

Data are reported on 1,755 synthetic compounds which were tested in the CCNSC pri@ry screens. A].mogt a].]. of the conpcxu@s were tested in Sarcon@ 180, @.rcix@na755, LeUkemia 1210, and KB cells in cul ture; some tests were also carried out in Friend virus leukemia and Lewis lung carcinoma. I@ta are re ported only on compounds which have not demonstrated sufficient activity in these systems to ...

Antibodies against cell surface antigens of human sarcomas were detected by a complement-dependent cytotoxicity test. Exogenous rabbit complement was required. Sera were titrated in doubling dilutions to a 50% survival end point, relative to control sera. Test cells were obtained from 21 cell cultures derived from sarcoma specimens, and 9 cultures of non-sarcoma cells. Two lines of evidence ind...

Human influenza A(H3N2) viruses that predominated during the moderately severe 2014-2015 influenza season differed antigenically from the vaccine component, resulting in reduced vaccine effectiveness (VE). To examine antibody responses to 2014-2015 inactivated influenza vaccine (IIV) and live-attenuated influenza vaccine (LAIV) among children and adolescents, we collected sera before and after ...

This study evaluated the cytotoxicity, antimicrobial and physicochemical properties of root canal sealers incorporated with phytotherapic Uncaria tomentosa (UT). Unmodified AH Plus (Dentsply, DeTrey, Germany) MTA Fillapex (Angelus, Londrina, Brazil) were used as controls. UT was into Fillapex, at concentrations 2% 5% total weight these (w/w). Flowability, setting time, solubility following ISO ...

Antibodies against cell surface antigens of human sarcomas were detected by a complement-dependent cytotoxicity test. Exogenous rabbit complement was required. Sera were titrated in doubling dilutions to a 50% survival end point, relative to control sera. Test cells were obtained from 21 cell cultures derived from sarcoma specimens, and 9 cultures of non-sarcoma cells. Two lines of evidence ind...

The Ti/Zr-based metallic glasses (MGs) with various Cu contents are prepared, with nominal compositions of Ti45Zr40Si15 (Cu-free), Ti45Zr40Si10Cu5 (low-Cu), and Ti45Zr20Cu35 (high-Cu). The mechanical properties, corrosion resistance, and in-vitro biocompatibility of these MGs are investigated by means of nano-indentation, electrochemical analyses, MTS assays and inductively coupled plasma mass ...

this study aimed to evaluate the cellular toxicity of two newly-released acrylic resins (futura gen and gc reline hard) in comparison with the conventional heat-cure resin (meliodent).sample discs from each acrylic resin were placed in 24-well culture plates along with l929 mouse fibroblast cell line. a mixture of the rpmi 1640 medium, antibiotics and 10% fbs was added to the plates and the spe...

introduction: root canal disinfection is an important step in regenerative endodontic treatments. an ideal irrigating solution must have high antimicrobial activity and minimum cytotoxicity. this study sought to assess the effect of some irrigating solutions on stem cells from the human apical papilla (scap) after different periods of exposure. methods and materials: stem cells were isolated fr...