The main goal of this work was to report the synthesis, characterization, and cytotoxicity study a novel copper(II)-sunitinib complex, CuSun. It has been synthesized characterized in solid state solution by different methods (such as DFT, FTIR, Raman, UV-vis, EPR, NMR, etc.). solid-state molecular structure trichlorosunitinibcopper(II), where sunitinib: N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluor...

background fish cell lines are advantageous alternatives to mammalian cell lines for carrying out in vitro research. they are used extensively for the study of fish biology, physiology and toxicology, and more recently for germplasm conservation of important fish species. objectives the present study aims to establish and characterize a novel fish cell line from muscle tissue of wallago attu ca...

Highly sensitive reporter-gene assays have been developed that allow the precise quantification of both direct vascular endothelial growth factor-A neutralizing activity bevacizumab and ability to activate antibody dependent cellular cytotoxicity. The use these analyzes samples from patients with ovarian cancer following four cycle treatment revealed a close correlation between cytotoxicity act...