Figure 1. Annual incidence of cytomegalovirus (CMV) disease among the southern Alberta population of HIV-infected individuals, 1987–2005. The introduction of HAART was immediately followed by a drastic decrease in the incidence of CMV disease among the HIV-infected population of southern Alberta ( , by nonpooled Student’s t test). There were 4 diagnoses of CMV disease among 15 patients receivin...

BACKGROUND: Congenital cytomegalovirus (CMV) infection is the leading infectious cause of neurologic disabilities and sensorineural hearing loss in children. Sensorineural hearing loss prevalence in CMV suggests a viral tropism for the inner ear. Vestibular disorders induced by CMV infection are underestimated. This is the largest and most thorough study to assess the incidence of vestibular di...

Abstract We present a case report of an immunocompromised adult with cytomegalovirus infection and APLA positivity complicated by multiple large arterial thrombi. This is rare presentation as most the cases reported earlier have been venous thrombosis, thus demonstrating propensity CMV to induce thrombosis either directly or indirectly.

Cytomegalovirus (CMV) infection is a risk factor for acute and chronic rejection of transplanted organs. We evaluated, using immunohistochemistry, the presence of CMV pp65 matrix protein in cardiac allografts and its association with acute rejection. CMV pp65 was found in 83/88 (94%) endomyocardial biopsies obtained from 35 patients and the presence of CMV was confirmed in selected patients by ...

The data shows the aqueous humor cytokine profiling results acquired in a small cohort of 17 HIV patients clinically diagnosed with Cytomegalovirus retinitis using the FlexMAP 3D (Luminex®) platform using the Milliplex Human Cytokine® kit. Aqueous humor samples were collected from these patients at different time points (pre-treatment and at 4-weekly intervals through the 12-week course of intr...

BACKGROUND Since early 60's that Cytomegalovirus was studied for its possible role in cervical cancer development. Despite several decades of studies and the description of CMV DNA in cervical samples, it is still doubtful what is the prevalence of Cytomegalovirus in cervix and if CMV can act as a co-factor in cervical carcinogenesis. METHODS In this Systematic Review we intend to summarize t...

OBJECTIVES To investigate the significance of cytomegalovirus (CMV) in mucocutaneous lesions in patients with human immunodeficiency virus (HIV), and to elucidate its pathogenetic role in lesions genesis. DESIGN Retrospective (study 1) and prospective (studies 2 and 3) surveys. SETTING Departments of Dermatology, Pathology, and Microbiology at a university hospital in Madrid, Spain. PATIE...

BACKGROUND Cytomegalovirus is the most common cause of congenital infection in the developed countries. Gastrointestinal involvement has been extensively described in both adult and paediatric immunocompromised patients but it is infrequent in congenital or perinatal CMV infection. CASE PRESENTATION We report on a case of coexistent congenital Cytomegalovirus infection with intestinal malrota...

Blood samples from human immunodeficiency virus (HIV)-positive patients were monitored for cytomegalovirus (CMV), human herpesvirus 6 (HHV-6), and HHV-7 by PCR. We detected CMV in 17% of the patients, HHV-6 in 6%, and HHV-7 in 3%. The viral loads of CMV were significantly higher than those of HHV-6 (P = 0.007) or HHV-7 (P = 0.01). Detection of CMV and HHV-6 was associated with low and high CD4 ...

We report that in a population of allogeneic stem cell transplant recipients, determination of the viral doubling time (dt) of the cytomegalovirus (CMV) DNA plasma load predicted the eventual need for inception of preemptive antiviral therapy, whereas the level of the initial plasma CMV DNA load did not. The data thus indicated that determination of the dt of CMV DNA may be useful in the therap...