Objective(s) The main objective of this study was to investigate the status of chromosome stability in 3 human-mouse hybridoma cell lines over a period of time in various passages. Materials and Methods Metaphase spreads from 3 human-mouse cell lines (HF2X653, SPMO-4 and F3B6) that had been cultured in 4 successive passages, from 1 to 4 weeks, were prepared and analyzed. Metaphase chromosome...

a cytogenetic study was performed on m4 generation of gamma irradiated lines of shirpan cultivar of tetraploid cotton (gossypium hirsutum l.). a significant difference was observed in cytogenetical characteristics such as the number and type of quadrivalents as well as percentage of cells showing abnormality among the irradiated and non irradiated lines. cytomixis and post- pachytene diffuse st...