under prolonged diabetic conditions, hba1c is produced from normal hemoglobin (hba0) through a non-enzymatic glycosylation or glycation, a process which enhances the hemoglobin susceptibility to be auto-oxidized to methemoglobin (methb). here we are reporting that the non-enzymatic reaction between fructose and methb (methb fructation) induces significant changes in the globin structure and deg...

Cyclic bis(3'-5')diguanylic acid (cyclic-di-GMP) functions as a second messenger in diverse species of bacteria to trigger wide-ranging physiological changes. We measured cyclic-di-GMP and its structural analogs such as cyclic bis(3'-5')guanylic/adenylic acid (cyclic-GpAp), cyclic bis(3'-5')guanylic/inosinic acid (cyclic-GpIp) and monophosphorothioic acid of cyclic-di-GMP (cyclic-GpGps) for eff...

Cyclic AMP and cyclic GMP were released into the growth medium of mycelia of Neurospora crassa wild-type strains St.L.74A and Em5297a and by white collar-1 and white collar-2 mutant strains. After growth for 6 days at 18 degrees C, there were 2.19 (St.L.74A), 5.83 (Em5297a), 1.38 (white collar-1), and 1.10 (white collar-2) nanomoles of cyclic AMP per gram dry weight of mycelia in the growth med...

Ajwain is one of the medicinal plants, which the highest composition is thymol, as a strong antioxidant respect to the obtained chromatograms of GC/MS. The antioxidant activity of the Ajwain is measured by square wave voltammetry method and cyclic voltammetry method and 2, 2-Diphenyl-1-picrylhydrazyl (DPPH) method in at the specific concentrations of 1%, 1.5%, 2% and 2.5% and constant pH. The r...

A cyclic AMP-binding protein with a native molecular weight calculated to be 82,000 was purified 2,000-fold from Neurospora crassa. The apparent subunit molecular weight was 47,000 by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, suggesting that the native protein exists as a dimer of identically sized subunits. The 8-N3-cyclic [32P]AMP-labeled protein appeared as a doublet upon tw...

Adenosine-3',5'-cyclic monophosphate was shown to be the compound found in Escherichia coli responsible for the attraction of the amoebae of the cellular slime mold Dictyostelium discoideum. A number of other nucleotides were tested and the following were active: tubercidin-3',5'-cyclic monophosphate, N(6)-2'-O-dibutyryl-adenosine-3',5'-cyclic monophosphate, 5'-methylene adenosine-3',5'-cyclic ...

Permeabilized, MgATP-reactivated cells of Paramecium (models) respond to cyclic AMP and cyclic GMP by increasing forward swimming speed. In association with the motile response, cyclic AMP and 8-bromo-cyclic GMP (8-Br-cyclic GMP) stimulated protein phosphorylation. Cyclic AMP addition to permeabilized cells reproducibly stimulated the phosphorylation of 10 proteins, ranging in molecular weight ...

a group $g$ is said to be a c-tidy group if for every element $x in g setminus k(g)$‎, ‎the set $cyc(x)=lbrace y in g mid langle x‎, ‎y rangle ; {rm is ; cyclic} rbrace$ is a cyclic subgroup of $g$‎, ‎where $k(g)=underset{x in g}bigcap cyc(x)$‎. ‎in this short note we determine the structure of finite c-tidy groups‎.