نتایج جستجو برای: cyclic 1
تعداد نتایج: 2822402 فیلتر نتایج به سال:
Cyclic-di-AMP is a relative newcomer to the large family of nucleotide-based signaling molecules, which notably includes cyclic-AMP, cyclic-di-GMP, and ppGpp(p) (1). Cyclic-diAMP was first implicated as a possible signaling molecule when it was unexpectedly found bound to the active site of the Bacillus subtilis DisA protein, the prototype for a diverse family of diadenyl cyclases (DAC) (2). Sh...
Stufken (1993) first introduced cyclic polygonal designs (CPDs) (in terms of cyclic balanced sampling plans excluding adjacent units (CBSAs)) for joint distance α ≥ 2. Wei (2002) first suggested the use of Langford sequence for the existence and construction of CPDs with block size k = 3 and λ = 1 for arbitrary α . Zhang and Chang (2005b) used Langford and extended Langford sequence, and constr...
Sensitive and specific radioimmunoassays have been developed for cyclic adenosine 3’, 5’-monophosphate (CAMP), cyclic guanosine 3’ ,5’-monophosphate (cGMP), cyclic inosine 3’ ,5’-monophosphate (cIMP), and cyclic uridine 3’, 5’monophosphate (cUMP). These assays are based upon competition of the cyclic nucleotide with isotopically labeled cyclic nucleotide derivatives for binding sites on specifi...
in a large scale cyclic storage system ,as the number of rule parameters and/or number of operating period increase, general purpose gradient-based nlp solvers and/or genetic algorithms may loose their merits in finding optimally feasible solution to the problem. in these cases hybrid ga which decomposes the main problem into two manageable sub-problems with an iterative scheme between ga and l...
Embryonic stem (ES) cells are exposed to fluid-mechanical forces, such as cyclic strain and shear stress, during the process of embryonic development but much remains to be elucidated concerning the role of fluid-mechanical forces in ES cell differentiation. Here, we show that cyclic strain induces vascular smooth muscle cell (VSMC) differentiation in murine ES cells. Flk-1-positive (Flk-1+) ES...
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