how to cite this article: rashnonejad a, onay h, atik t, atan sahin o, gokben s, tekgul h, ozkinay f. molecular genetic analysis of survival motor neuron gene in 460 turkish cases with suspicious spinal muscular atrophy disease. iran j child neurol. autumn 2016; 10(4):30-35. abstract objective to describe 12 yr experience of molecular genetic diagnosis of spinal muscular atrophy (sma) in 460 ca...

objective(s):fumonisins are a group of toxic and carcinogenic mycotoxins, which contaminate the grains and their products. the aim of this study was to examine the apoptotic and proliferative activity of mouse gastric mucosa following administration of fumonisin b1 (fb1).    materials and methods: twenty-nine female mice divided into treatment (n=15) and control (n=14) groups. the treatment gro...

Many studies have documented cognitive deficits, especially spatial in patients with some form of vestibular loss. Almost 20 years ago, hippocampal (HPC) atrophy was reported to be correlated memory deficits such and the idea has gradually emerged that HPC may causally responsible for deficits. However, results volume following loss not always been consistent, a number no evidence atrophy. This...

objective: this study was conducted to determine the changes in the insular cortex in alcohol dependent subjects, and to compare the same with controls, the associated clinical findings. methods: the study group consisted of 30 subjects with alcohol dependence syndrome (ads) selected randomly from the out patient services of the department of psychiatry of a tertiary care hospital. the control ...

Objectives: To investigate the safety and efficacy of Contractubex® administration to hypertrophic scars in routine out-patient practice and to compare it to corticosteroid treatment. Patients and Methods: This was a multicenter, retrospective cohort study, based on 38 randomly selected practices representatively distributed in Germany, including dermatologists and general practitioners. Data f...

sarcoidosis is multi organ disease with cutaneous manifestation in 20%-35% patients. cutaneous sarcoidosis has variable manifestations that make it difficult to diagnose. so clinical, histopathologic and laboratory evaluation is needed for diagnosis. most of cutaneous lesions presents as nodul, maculopapule and plaque. morpheaform lesion is a rare presentation of cutaneous sarcoidosis. this cas...

occurrence of cutaneous metastasis of gastrointestinal cancer is uncommon, with a reported frequency of less than 5 percent.they can occur as the first sign of disease recurrence in a treated patient or as a sign of terminal disseminated cancer or rarely as the first manifestation of an occult malignancy. the cases reported here represent three different manifestation of cutaneous metastasis of...