High-speed counter-current chromatography (HSCCC) was applied to isolate and purify bioactive compounds in the essential oil of the rhizomes of Curcuma wenyujin. Two sesquiterpenes germacrone and curdione were successfully isolated and purified using two-phase solvent system composed of petroleum ether-ethanol-diethyl ether-water (5/4/0.5/1, v/v) in tail to head elution mode. 62 mg of germacron...

Plant density was varied with P, Ca, Mg, and KNO3 in a multifactor experiment to improve Curcuma longa L. micropropagation, biomass and microrhizome development in fed-batch liquid culture. The experiment had two paired D-optimal designs, testing sucrose fed-batch and nutrient sucrose fed-batch techniques. When sucrose became depleted, volume was restored to 5% m/v sucrose in 200 ml of modified...

Bacterial cellulose- Curcuma Longa Linn from acetobacter xylinum has been produced. The aim of research: To isolate Cellulose-Curcuma Acetobacter and to improve activity catalitic bacterial cellulose. Morphology properties was carried out on sample cellulose extract. This characteristic test by Scanning Electron Microscope (SEM).

Background: Natural products such as herbs, fruits, spices, beverages, vegetables are becoming more popular among scientific community and consumers because of their potential to arrest the effect of free radicals in human system. This study determined the total antioxidant capacity of ten selected species of Zingiberaceae (Ginger) used as spices and for medicinal purposes in Southeast Asia. Ma...

Background: Different treatment and protec ve approaches for radia oninduced oral mucosi s have been prac ced and have varie es of success. Of which, radioprotec ve agents, synthe c or natural, have been of great interest for researchers. This study aims to evaluate the effect of curcuma longa topical gel as a herbal produc on on mucosi s induced by radia on therapy of head and neck cancers. Ma...

Curcuma longa is well known for its use as spice and medicine. The remarkable feature of the plant is the presence of rhizome, which provides an interesting habitat for association by various groups of bacteria. Some of these associated endophytic bacteria can have growth-promoting effects. In the current study, two species of endophytic Paenibacillus has been identified from the rhizome as ind...

Extracts from 11 plant species belonging to the Zingiberaceae were tested for antifungal activity using disc diffusion bioassays. Extracts from several members, especially Alpinia galanga, Curcuma zedoaria and Zingiber purpureum, were found to have pronounced inhibitory activities against a wide variety of human pathogenic fungi, including strains resistant to the common antifungals amphoterici...

Numerous adverse effects limit the applicability of mitoxantrone for the treatment of drug-resistant tumors, including carcinosarcoma. Here, we estimated the additive effects of mitoxantrone and curcumin, a plant-derived biomolecule isolated from Curcuma longa, on the neoplastic and invasive potential of carcinosarcoma cells in vitro. Curcumin augmented the cytostatic, cytotoxic and anti-invasi...

Objective: Cancer is one of the most dreadful diseases which is globally distributed among the world’s population. Cancer occurs due to excessive free radical damage, which ultimately causes damage to the genetic material DNA, protein, and lipids. This DNA damage leads to mutations that cause normal cells to transform into a cancer cell. Breast cancer is the major health problem among women in ...