BACKGROUND Close interaction between retinal pigment epithelium (RPE) and photoreceptors plays an essential role in visual function. The objective of this study is to determine the effects of RPE cells in the differentiation of progenitor derived human embryonic stem cells (hESC) into retinal cells; we developed in vitro co-culture models and compare these models to investigate in which model t...

OBJECTIVES To describe the early symptoms of pulmonary tuberculosis (TB) when the chest radiograph (CXR) is normal. SETTING Centralized, provincial TB control program. SUBJECTS Twenty-five patients with culture-positive pulmonary TB and a normal CXR were identified from a review of 518 consecutive patients with culture-positive pulmonary TB in the province of Saskatchewan from January 1, 19...

Studies reveal that there exists much interaction and communication between bacterial cells, with parts of these social behaviors depending on cell-cell contacts. The cell-cell contact has proved to be crucial for determining various biochemical processes. However, for cell culture with relatively low cell concentration, it is difficult to precisely control and retain the contact of a small gro...

Cultural and creative tourism is emerging in industry with the potential to be sustainable as an important carrier of traditional culture. This study adopts stimulus–response theory a cultural integration perspective investigate how tourists’ memories, contact, attitude culture affect their revisit intention. With questionnaire survey responses from 651 tourists structural equation modeling met...

We describe a direct way of measuring contact inhibition of locomotion by analysing the changes in motion of pairs of colliding cells. This allows values to be assigned to each type of cell in mixed collisions and will enable certain hypotheses about the relationship between contact inhibition and invasion in culture to be tested critically. We find that fibrosarcoma (FS9) cells, on colliding w...

.................................................................................................................... iii Summary in swedish.................................................................................................. iv

PURPOSE Diagnosis of tuberculosis (TB) in children is more challenging than in adults. This study aimed to describe demographical, clinical and laboratory findings of children diagnosed with tuberculosis in Turkey, including the issues of contact tracing, culture positivity and forms of the disease. MATERIALS AND METHODS Clinical and laboratory data of 51 children with a mean age of 8.0±4.6 y...

This study was initiated to characterize the regulation and secretion of ExoS by Pseudomonas aeruginosa during contact with eukaryotic cells. The production of ExoS was monitored by a sensitive ADP-ribosyltransferase activity assay, and specific activities were calculated for supernatant and cell-associated fractions. Time course analysis indicated that ExoS was produced after a lag period, sug...