Luc Demortier The Rockefeller University, New York, NY 10021, U.S.A. Abstract The standard Bayesian treatment of systematic uncertainties is to integrate out the corresponding nuisance parameters from the joint posterior density for all parameters. We apply this formalism to measurements in which the data cannot distinguish between nuisance parameters and parameters of interest, and show that i...

Abstract. MAP estimators and HPD credible sets are often criticized in the literature because of paradoxical behaviour due to a lack of invariance under reparametrization. In this paper, we propose a new version of MAP estimators and HPD credible sets that avoid this undesirable feature. Moreover, in the special case of non-informative prior, the new MAP estimators coincide with the invariant f...

This article discusses medico-legal aspects in anesthesia. It underlines the standards of care by which anesthesiologists should abide by, as well as define malpractice, its causes, and ways to avoid it. The role of the expert witness is explained and the ethical guidelines to follow are outlined.

I propose a theory of the passive that combines aspects of the principles and parameters analysis (no specific rules, no downward movement) and Chomsky’s (1957) Syntactic Structures analysis (the arguments in the passive are generated in the same positions as they are in the active).

A large number of molecular mechanisms exist to ensure the continued function of perturbed cells. Here we explore a range of mechanisms of molecular robustness. A theory of robustness is proposed in which mechanisms are classified into those that purge damage, and those that buffer damage. The strategy upon which a system settles, is a function of the cost of purgation, and thereby a function o...

Directive 2008/98/EC released by the European Union represents a significant step forward in all relevant aspects of waste management. Under the already established, extended produced responsibility (EPR) principle, new policies have been enunciated to continuously achieve better overall environmental performance of key products throughout their life phases. This paper discusses how the directi...