A ribonuclease helps the ER get in shape S chwarz and Blower reveal that a calcium-regulated ribonuclease promotes the formation of tubular ER networks. By triggering a wave of intracellular calcium, fertilization induces dramatic changes in the internal organization and protein expression pattern of oocytes. Schwarz and Blower discovered that increased calcium levels activate a ribonuclease ca...

Anomalous self-assembly of the Aβ peptide into fibrillar amyloid deposits is strongly correlated with the development of Alzheimer's disease. Aβ fibril extension follows a template guided "dock and lock" mechanism where polymerisation is catalysed by the fibrillar ends. Using surface plasmon resonance (SPR) and quenched hydrogen-deuterium exchange NMR (H/D-exchange NMR), we have analysed the fi...

Software deployment is an evolving collection of interrelated processes such as release, install, adapt, reconfigure, update, activate, deactivate, remove, and retire. The connectivity of large networks, such as the Internet, is affecting how software deployment is being performed. To take full advantage of this connectivity, new software deployment technologies must be introduced in order to s...

Cross-docking is a new warehousing policy in logistics which is widely used all over the world and attracts many researchers attention to study about in last decade. In the literature, economic aspects has been often studied, while one of the most significant factors for being successful in the competitive global market is improving quality of customer servicing and focusing on customer satisfa...