Introduction Inflammatory bowel disease (IBD) consists of ulcerative colitis (UC), Crohn disease (CD), and indeterminate colitis. While sharing many clinical features, ulcerative colitis and Crohn disease are considered separate entities with unique characteristics. Due to the chronic nature of these diseases, frequent and repeated imaging is often necessary for diagnosis and therapeutic planni...

Numerous similarities between Crohn's disease and sarcoidosis are being reported. Because of previous findings of culturable mycobacteriophage in the serum of many patients with sarcoidosis, mycobacteriophages were sought in serum of patients with Crohn's disease. No difference was found in the frequency of positive cultures between patients with Crohn's disease and normal control subjects.

Although the use of CAM in pediatric CD is common, quality evidence-based research is limited. There is clearly a need for further randomized controlled trials. The role of psychosocial distress in children with CD should not be overlooked and thus biobehavioral techniques should be considered and incorporated when possible. Considering the potential for growth failure and need for surgical int...

The typical macroscopic features of Crohn's disease have been well described and are widely regarded as sufficient to diagnose the disease at laparotomy. We report six patients undergoing laparotomy for symptomatic Crohn's disease, shown radiologically, who were found to have macroscopically normal small bowel despite careful examination of the bowel by an experienced surgeon. In four cases res...

PURPOSE Crohn disease is characterized by high rates of recurrence and reoperations. However, few studies have investigated long-term surgical outcomes in Asian populations. We investigated risk factors for reoperation, particularly those associated with anti-tumor necrosis factor-α (anti-TNF-α) antibody use, and long-term follow-up results. METHODS We reviewed the records of 148 patients (10...

rohn disease is a chronic inflammatory condition of the bowel characterized by periods of quiescence and inflammatory activity or “disease flares.” Although genetic factors, dysbiosis, and altered immunity are implicated in inflammatory bowel disease, the etiology is unknown.1 The peak age of onset is early in life, between 15 and 40 years, thus affecting patients during their most productive y...

BACKGROUND The reported prevalence of gallstone disease (GD), defined as current gallstones or previous cholecystectomy for gallstones, in patients with Crohn disease ranges from 13% to 34%. The aim of this study was to characterize the still undefined risk factors of this complication. METHODS A total of 330 consecutive patients with Crohn disease (189 males and 141 females aged 17-82 years,...