Current treatment based algorithms for NSCLC are often derived from studies that were conducted prior to the extensive wealth of knowledge that was gained by subtyping lung cancer into distinct molecular entities. New studies are now helping to refine strategies for second-line approaches in EGFR-mutated, Alk-rearranged, as well as in EGFR/Alk-unmutated tumours. This review will focus on treatm...

In the past 2 decades, the literature has been flooded with studies that attempt to define historical, physical, or laboratory findings that alone or in some combination can be used to riskstratify emergency department (ED) patients. The rationale for this work is that such risk-stratification tools will identify lowrisk patients who do not require additional evaluation during their ED visit. B...

When public health decisionmakers turned to quarantine during the recent severe acute respiratory syndrome (SARS) epidemic, difficult questions were raised about the legitimacy and acceptability of restrictive measures to attain public health goals. SARS also brought to light how scientific uncertainty can permeate public health decisionmaking, leading us to think about the relationship between...

Compressed Abstract: This paper submits an approach to broadly non-truth-conditional aspects of meaning in natural language which interprets`pragmatics' substantively: in the way of C.S. Peirce and F.P. Ramsey, as a synonym for decision-theory. We outline (i) basic assumptions, (ii) some relations to other approaches, (iii) a range of results wide enough to justify the termàpproach'. A key noti...

A conceptual design of an organizational decision support system (ODSS) is proposed for the limited domain of hospital-based clinical decisionmaking (H-CDM). The design is a first step in the research program to evaluate the viability of an ODSS for H-CDM. The design is also used as a basis for evaluating two other issues. First, the adequacy of broader conceptualizations of ODSS proposed in pr...

This article analyzed the decision-making power of women in childbirth expressed discursive practices nurses and resident physicians area obstetrics. Qualitative study with 22 residents a maternity hospital. Data were collected through interviews submitted to discourse analysis following Michel Foucault’s views. The focus on risk control normalization cooperative behavior parturient woman, culm...

In this paper, we examine the concepts of norms and roles in multiagency. After a general treatment of relationships between goals, roles, and norms in a rational utilitarian agent, we turn to team-oriented decisionmaking, which is facilitated by notions of positional role hierarchies and group roles. We use simulated Robocup as a case study for team oriented decisionmaking and illustrated role...