One hundred and forty-four years elapsed between the publication of Copernicus’s De Revolutionibus, which opened the great scientific revolution of the XVII century, and the publication of Newton’s Principia, the final synthesis that brought that revolution to a spectacularly successful end. During those hundred and forty-four years, the basic grammar for understanding the physical world change...

Introduction: The aim of the present study was to evaluate the effect of exercise training and L-arginine supplementation on oxidative stress and systolic ventricular function in rats with myocardial infarction (MI). Methods: Four weeks after the surgically-induced MI, 40 male Wistar rats were randomly assigned to the following 4 groups (n=10): MI-sedentary control (Sed) MI-exercise (Ex) MI-...

Summary The article explores how two early modern Ukrainian preachers, Stefan Javors’kyj and Antonij Radyvylovs’kyj, adapt combine Neoplatonic philosophy, Aristotelian epistemology, the antique, Renaissance idea of poetry painting as sister arts to create pictorial texts that translate some material manifestations contemporary visual culture such emblem into written form; these images – both ve...

Background: During the aging process, muscle atrophy and neuromuscular junction remodeling are inevitable. The present study aimed to clarify whether low-intensity aerobic exercise along with limb blood-flow restriction (BFR) could improve aging-induced muscle atrophy and nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction.Methods: Forty-eight male Wistar rats, aged 23–24 m...

Venture capital (VC) is a relatively recent addition to the US national system of innovation (NSI). Tracing the history of the VC industry in the US provides an interesting example of how NSIs can add new institutions, and in the process be transformed. The history encompasses important exogenous events, endogenous developments, and actions by individual actors. The story of the development of ...

Introduction: Renal ischemia/reperfusion (I/R) injury due to reactive oxygen species (ROS) formation is the main cause of acute kidney damage. Nitric oxide (NO) biosynthesis and oxidative stress are closely related to the pathogenesis of renal I/R injury. This study was undertaken to determine the effects of L-arginine (L-arg) as NO donor and aerobic exercise (EX) and also the combination of L-...

background: to evaluate the effect of exendine-4 (ex-4), a glucagon-like peptide 1 (glp-1) receptor agonist, on the differentiation of insulin-secreting cells (ipcs) from rat adipose-derived mesenchymal stem cells(admscs). materials and methods: in this experimental study, admscs were isolated from rat adipose tissue and exposed to induction media with or without ex-4. after induction, the exis...