There is no single diabetic neuropathy. A wide variety of syndromes involving the peripheral nerves may be encountered in patients with diabetes mellitus, implying a correspondingly diverse range of underlying causative mechanisms. The classification of the diabetic neuropathies is not yet finalised and has required successive modifications in the light of accumulating knowledge. The scheme fav...

There is increasing evidence that monoclonal proteins are implicated in the development of peripheral neuropathy. Approximately ten percent of patients with peripheral neuropathy of unknown cause have a monoclonal protein and this rate is significantly higher than prevalence rates of monoclonal protein in comparable segments of the general population. Extensive clinical, electrophysiological an...

SYNOPSIS Single fibre electromyography was carried out in patients with polyneuropathy due to uraemia, diabetes, and alcohol. In the two former groups the fibre density within the motor unit and the impulse transmission were mainly normal. In the latter group the fibre density was significantly increased as signs of reinnervation. Impulse transmission was impaired in a number of the action pote...

Paraneoplastic polyneuropathies are among the most common distal neurological complications of systemic cancer on the nervous system. All peripheral neuropathy types, such as demyelinating, axonal, motor, sensory, or autonomic, can present in association with cancer and can have a paraneoplastic etiology (1). Classical paraneoplastic peripheral neuropathy is typically a sensory neuropathy with ...

an association between the sicca syndrome and inflammatory polyneuropathy, and lends further support to the hypothesis that, like the sicca syndrome and systemic lupus erythematosus with which they are also associated,2 the inflammatory polyneuropathies have an auto-immune basis. Our patient developed a clinical neuropathy at a time when symptoms of the sicca syndrome were minimal. This finding...

After a stay in intensive care, patients may suffer physiological after effects, such as muscle wasting, polyneuropathies, disturbed sleep, itching and poor mobility. The care that patients receive whilst on intensive care may contribute to the severity of some of these physical problems. Raising awareness amongst critical care nurses may help reduce the severity of some of the physiological af...

Background: Central Nervous System (CNS) relapse in acute lymphoblastic leukemia was significantly decreased due to the use of new chemotherapyeutic agents, Intrathecal chemotherapy and cranial irradiation. The purpose of this study was to compare the effectiveness of intrathecal (IT) CNS chemotherapy alone versus combination of IT chemotherapy with cranial irradiation for prevention of CNS rel...

Reported are a total of 81 microsurgical operations for cranial nerve root decompression comprising of 66 trigeminal, 10 facial, one vestibular, one vagus and three accessory nerve dysfunction syndromes from 1983 to 1990. Almost all cases of trigeminal neuralgia (TNG) secondary to vascular (59 cases) and minute mass (10 cases) compression, and those with hemifacial spasm (HFS) (nine out o...