Corticobasal degeneration (CBD) is a distinct neurodegenerative disorder characterized by widespread neuronal and glial accumulation of abnormally phosphorylated tau protein. Patients with CBD often present with corticobasal syndrome (CBS) showing impairment of the motor system, cognition, or both. Several studies demonstrate that they may also present with progressive supranuclear palsy syndro...

BACKGROUND The serum level of gamma glutaryl transferase and alkaline phosphatase is raised in acute calculus cholecystitis and common bile duct stone. However, the rise in serum level of these enzymes in acute cholecystitis implies stone in the common bile duct is not well studied. Thus, it may lead to retained CBD stone on one side and unnecessary CBD exploration on the other during emergency...

BACKGROUND To repair fractures with large bone defects or gaps, demineralized allogenic bone matrix (DBM) is often applied to the fracture site. However, studies have shown that the use of DBM alone has limited efficacy for repairing fractures. In the present study, we developed an allogenic demineralized bone powder (DBP) with basic fibroblast-derived growth factor containing a polycystic kidn...

RATIONALE Beryllium continues to have a wide range of industrial applications. Exposure to beryllium can lead to sensitization (BeS) and chronic beryllium disease (CBD). OBJECTIVES The purpose of this statement is to increase awareness and knowledge about beryllium exposure, BeS, and CBD. METHODS Evidence was identified by a search of MEDLINE. The committee then summarized the evidence, dre...

AIMS The protective effects of cannabidiol (CBD) have been widely shown in preclinical models and have translated into medicines for the treatment of multiple sclerosis and epilepsy. However, the direct vascular effects of CBD in humans are unknown. METHODS AND RESULTS Using wire myography, the vascular effects of CBD were assessed in human mesenteric arteries, and the mechanisms of action pr...

BACKGROUND AND PURPOSE Carotid bulb diaphragm (CBD) has been described in young carotid ischemic stroke (CIS) patients, especially in blacks. However, the prevalence of CBD in CIS patients is unknown, and whether CBD is a risk factor for CIS remains unclear. We assessed the association between CBD and incident CIS in a population-based study. METHODS We selected all young (<55 years) CIS pati...

To investigate the effect of repair of bioabsorbable poly(lactide) (PLA) biliary stent in common bile duct (CBD) transection injury in canine prior to the clinical application. Circular tubing CBD stent was prepared by melt extraction technique using PLA. A transection incision was made on CBD of the normal canine, and then closed the incision with laser welding followed the implantation of PLA...

Introduction The recurrence rate of choledocholithiasis after endoscopic stone extraction differs from 6.4% to 24%. Although the etiology of stone recurrence after initial ERCP has not been fully elucidated, some risk factors for stone recurrence have been reported: a common bile duct (CBD) dilatation, periampullary diverticula (PAD), pneumobilia, and acute CBD angulation. The early detection a...

This research attempts to span the gap between the AI in medicine (AIM) and consistency-based diagnosis (CBD) communities by applying CBD to physiology. The highly-regulated nature of physiological systems challenges standard CBD algorithms, which are not tailored for complex dynamic systems. To combat this problem, we separate static from dynamic analysis, so that CBD is performed over the ste...