نتایج جستجو برای: cp utr

تعداد نتایج: 42335  

Journal: :گوارش 0
reza ghanbari mehrdad ravanshad seyedunes hosseini kiana shahzamani

background: hepatitis g virus (gbv-c) is a single strand rnapositive virus and is a member of flaviviridae family. infection with the virus is prevalent add has worldwide distribution. accurate diagnosis of the virus is very important, because of co-infection with other important viruses like hcv, hbv and hiv, it may influence on pathogenesis, disease progression and response to viral therapy. ...

2018
Sheng-Yong Luo Qing-Hua Xu Gong Peng Zhi-Wu Chen

Objectives Total flavones from Rhododendron simsii Planch. (TFR) are the effective part extracted from the flowers of Rhododendron simsii Planch. and have obvious protective effects against cerebral ischemic or myocardial injuries in rabbits and rats. However, their mechanism of cardioprotection is still unrevealed. Therefore, the present study was designed to investigate the effect of TFR on m...

Journal: :Nucleic Acids Research 2005
Zeping Wang Matt Weaver Nancy S. Magnuson

The serine/threonine kinase pim-1 mRNA contains a long and G/C rich 5'-untranslated region (5'-UTR). Previous work suggested that the pim-1 5'-UTR harbors an internal ribosomal entry site (IRES) allowing for internal initiation of translation. However, several previously reported eukaryotic IRES elements actually contain cryptic promoter activity. To test whether an IRES or a cryptic promoter i...

Journal: :Journal of virology 2005
Anice C Lowen Richard M Elliott

Bunyamwera virus (BUNV) is the prototype of the genus Orthobunyavirus and the family Bunyaviridae. BUNV has a tripartite genome of negative-sense RNA composed of small (S), medium (M), and large (L) segments. Partially complementary untranslated regions (UTRs) flank the coding region of each segment. The terminal 11 nucleotides of these UTRs are conserved between the three segments and througho...

Journal: :Blood 2013
Yong Li Michael W Gordon Zijun Y Xu-Monette Carlo Visco Alexander Tzankov Dehui Zou Lugui Qiu Santiago Montes-Moreno Karen Dybkaer Attilio Orazi Youli Zu Govind Bhagat Kristy L Richards Eric D Hsi William W L Choi J Han van Krieken Qin Huang Weiyun Ai Maurilio Ponzoni Andrés J M Ferreri Jane N Winter Ronald S Go Miguel A Piris Michael B Møller Lin Wu Michael Wang Kenneth S Ramos L Jeffrey Medeiros Ken H Young

We identified multiple single nucleotide variants (SNVs) in the TP53 3' untranslated region (3'UTR) in tumor specimens from 244 patients with diffuse large B-cell lymphoma (DLBCL). Patients carrying a wild-type TP53 coding sequence (CDS) and 1 or more 3'UTR SNVs had a better 5-year survival rate than patients carrying a wild-type CDS and the reference 3'UTR, yet there is no statistically signif...

Journal: :American journal of physiology. Cell physiology 2000
W W Ashley B Russell

We tested the hypothesis that the beta-myosin heavy chain (beta-MHC) 3'-untranslated region (UTR) mediates decreased protein expression after tenotomy of the rat soleus. We also tested the hypothesis that decreased protein expression is the result of RNA-protein interactions within the 3'-UTR. beta-MHC was chosen for study because of its critical role in the function of postural muscles such as...

2014
Wendy Espinosa-Hernández Dora Velez-Uriza Jesús Valdés Cristina Vélez-Del Valle Juan Salas-Benito Rebeca Martínez-Contreras Matilde García-Espítia Mariana Salas-Benito Tania Vega-Almeida Mónica De Nova-Ocampo

The 3' untranslated region (3'UTR) of human astroviruses (HAstV) consists of two hairpin structures (helix I and II) joined by a linker harboring a conserved PTB/hnRNP1 binding site. The identification and characterization of cellular proteins that interact with the 3'UTR of HAstV-8 virus will help to uncover cellular requirements for viral functions. To this end, mobility shift assays and UV c...

2000
WILLIAM W. ASHLEY

Ashley, William W., Jr. and Brenda Russell. Tenotomy decreases reporter protein synthesis via the 39-untranslated region of the b-myosin heavy chain mRNA. Am J Physiol Cell Physiol 279: C257–C265, 2000.—We tested the hypothesis that the b-myosin heavy chain (b-MHC) 39-untranslated region (UTR) mediates decreased protein expression after tenotomy of the rat soleus. We also tested the hypothesis ...

Journal: :iranian biomedical journal 0
مسعود صبوری قناد masoud sabouri ghannad علیرضا زمانی alireza zamani

background: hepatitis c is a global health problem. the exact mechanisms by which hepatitis c virus (hcv) can evade the host immune system have become controversial. whether hcv polyproteins modulate ifn signalling pathways or hcv proteins are responsible for such a property is the subject of interest. therefore, an efficient baculovirus delivery system was developed to introduce the whole geno...

Journal: :Microbes and Infectious Diseases (Print) 2021

The genome of severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) has an untranslated region (UTR) that enhances the replication and transcription RNA, subgenomic RNA (sgRNA) which encodes 4 structural proteins are essential for viral replication. host cell SARS CoV-2 expresses important enzyme called TMPRSS2 protease allows virus to invade cell. Peptide conjugated phosphorodiamidate m...

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