نتایج جستجو برای: cotinine

تعداد نتایج: 1928  

Kazemi A Nasr Esfahani MH Nejat S Rahimi A Ramezanzadeh F Saboor Naraghi AA Yavari P

Background: Cigarette smoke contains many oxidants and may alter the human reproduction by inducing oxidative stress (OS) in both active and passive smokers. This study was designed to evaluation the effect of environment tobacco smoke (ETS) exposure on oxidative stress in follicular follicle and assisted reproduction outcomes. Materials and Methods: A prospective study was carried out on 236 i...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011
Valéria Troncoso Baltar Wei W Xun Shu-Chun Chuang Caroline Relton Per Magne Ueland Stein Emil Vollset Øivind Midttun Mattias Johansson Nadia Slimani Mazda Jenab Françoise Clavel-Chapelon Marie-Christine Boutron-Ruault Guy Fagherazzi Rudolf Kaaks Sabine Rohrmann Heiner Boeing Cornelia Weikert H Bas Bueno-de-Mesquita Hendriek C Boshuizen Carla H van Gils Petra H M Peeters Antonio Agudo Aurelio Barricarte Carmen Navarro Laudina Rodríguez José Maria Huerta Castaño Nerea Larrañaga Maria José Sánchez Pérez Kay-Tee Khaw Nick Wareham Naomi E Allen Francesca Crowe Valentina Gallo Teresa Norat Giovanna Tagliabue Giovanna Masala Salvatore Panico Carlota Sacerdote Rosario Tumino Antonia Trichopoulou Pagona Lagiou Christina Bamia Torgny Rasmuson Göran Hallmans Nina Roswall Anne Tjønneland Elio Riboli Paul Brennan Paolo Vineis

BACKGROUND Several countries are discussing new legislation regarding the ban on smoking in public places, based on the growing evidence of the hazards of secondhand smoke (SHS) exposure. The objective of the present study is to quantitatively assess the relationship between smoking, SHS, and serum cotinine levels in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort...

Journal: :JAMA 1998
H F Krous F R Hauck

Context.—Cotinine, a metabolite of nicotine, is a marker of exposure to tobacco smoke. Previous studies suggest that non-Hispanic blacks have higher levels of serumcotinine thannon-Hispanicwhiteswhoreportsimilar levelsofcigarettesmoking. Objective.—To investigate differences in levels of serum cotinine in black, white, and Mexican American cigarette smokers in the US adult population. Design.—T...

2012
Michelle Sims Jennifer S. Mindell Martin J. Jarvis Colin Feyerabend Heather Wardle Anna Gilmore

BACKGROUND On 1 July 2007, smokefree legislation was implemented in England, which made virtually all enclosed public places and workplaces smokefree. OBJECTIVES We examined trends in and predictors of secondhand smoke exposure among nonsmoking adults to determine whether exposure changed after the introduction of smokefree legislation and whether these changes varied by socioeconomic status ...

2015
Daniel Bender Patrick Haubruck Sonja Boxriker Sebastian Korff Gerhard Schmidmaier Arash Moghaddam

PURPOSE In this level 1 diagnostic study, we analyzed the validity of subjective smoking status and, as secondary research question, the smoking cessation adherence in orthopedic patients during a routine hospital stay of nonunion patients by measuring serum cotinine. METHODS We included patients undergoing revision surgery due to nonunion of long bones. Patients were interviewed about their ...

2013
Masayoshi Tsuji Yayoi Mori Hideyuki Kanda Teruna Ito Tomoo Hidaka Tomohiro Kumagai Takehito Hayakawa Yoneatsu Osaki Tetsuhito Fukushima

Nicotine and cotinine in hair are good biomarkers for assessing long-term exposure to smoking. However, analytical devices such as GC/MS are associated with high cost and are not widely used. HPLC/UV is used widely in laboratories, but is unsuitable for measurement of minor constituents, except when using the column-switching method. Thus, we aimed to establish a simple, inexpensive and sensiti...

2012
Valentina Echeverria Moran

A greater incidence of tobacco consumption occurs among individuals with psychiatric conditions including post-traumatic stress disorder (PTSD), bipolar disorder, major depression, and schizophrenia, compared with the general population. Even when still controversial, it has been postulated that smoking is a form of self-medication that reduces psychiatric symptoms among individuals with these ...

Journal: :Tobacco control 2007
Dinusha Fernando Jefferson Fowles Alistair Woodward Annemarie Christophersen Stuart Dickson Matthew Hosking Richard Berezowski Rod A Lea

AIM To measure exposure to second-hand smoke (SHS) in New Zealand bars before and after comprehensive smoke-free legislation enacted on 10 December 2004. METHODS Cotinine is the main specific metabolite of nicotine and a well-established biomarker for SHS exposure. We measured cotinine levels in saliva of non-smoking volunteers before and after a 3 h visit to 30 randomly selected bars in 3 ci...

Journal: :Human molecular genetics 2009
Kaisu Keskitalo Ulla Broms Markku Heliövaara Samuli Ripatti Ida Surakka Markus Perola Janne Pitkäniemi Leena Peltonen Arpo Aromaa Jaakko Kaprio

A cluster of three nicotinic acetylcholine receptor genes on chromosome 15 (CHRNA5/CHRNA3/CHRNB4) has been shown to be associated with nicotine dependence and smoking quantity. The aim of this study was to clarify whether the variation at this locus regulates nicotine intake among smokers by using the level of a metabolite of nicotine, cotinine, as an outcome. The number of cigarettes smoked pe...

2017
Sehun Kim Si-Hyuck Kang Donghoon Han Sun-Hwa Kim Hee-Jun Kim JIN-Joo Park Youngjin Cho Yeonyee E. Yoon Kyung-Do Han Il-Young Oh Chang-Hwan Yoon Jung-Won Suh Hae-Young Lee Young-Seok Cho Tae-Jin Youn Goo-Yeong Cho In-Ho Chae Dong-Ju Choi Cheol-Ho Kim

OBJECTIVE Secondhand smoke exposure (SHSE) in nonsmokers has been associated with premature cardiovascular mortality and ischemic heart disease. We conducted a cross-sectional, population-based study evaluating the relationship between SHSE, measured by subjective and objective methods, and conventional cardiovascular risks such as blood pressure, lipid profiles, and fasting glucose. METHODS ...

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