With several candidate dengue vaccines under development, this is an important time to help stakeholders (e.g., policy makers, scientists, clinicians, and manufacturers) better understand the potential economic value (cost-effectiveness) of a dengue vaccine, especially while vaccine characteristics and strategies might be readily altered. We developed a decision analytic Markov simulation model...

HMG-CoA reductase inhibitors, commonly known as statins, are some of the most widely prescribed medications worldwide and have been shown to be effective at lowering cholesterol in numerous long-term prospective trials, yet there are significant limitations to their use. First, patients receiving statin therapy have relatively low levels of medication adherence compared with other drug classes....

Commercial poultry production is rapidly expanding worldwide to meet the needs of the increasing human population. Further, with the reduced cost and enhanced incomes the per capita poultry meat consumption is increasing. Many poor and middle class farmers in developing countries are taking up poultry to supplement their income and this industry has become a major income source to them. The ind...

BACKGROUND Cervical cancer, which is common in developing countries, is also a major health issue in Korea. Our aim was to evaluate the cost-effectiveness of Korea's National Cancer Screening Program (NCSP), implemented in 1999. MATERIALS AND METHODS The target population was Korean women 30 years or over who were invited to take part in the NCSP in 2002-2007. By merging NCSP records with Kor...

Product families and product platforms have been suggested as design strategies to serve heterogeneous markets via mass customization. Numerous, individual cost advantages of these strategies have been identified for various life cycle processes such as product design, manufacturing, or inventory. However, these advantages do not always occur simultaneously, and sometimes even counteract each o...

Estimating manufacturing costs of a new product or process soon after research and development (R&D) has commenced can provide a good indication of the project’s economic viability. “Early” estimates can be used to direct research efforts to promising opportunities for cost reduction, and allow businesses to better assign resources to new products. Although potentially compromised because some ...

Activity-Based Costing (ABC) represents an alternative paradigm to traditional cost accounting system and it often provides more accurate cost information for decision making such as product pricing, product mix, and make-orbuy decisions. ABC models the causal relationships between products and the resources used in their production and traces the cost of products according to the activities th...

Joint managed inventory is an advanced supply chain inventory management tool, which will effectively tackle the complicated problem between the inventory cost of supply chain and service level. The research on inventory model and its’ control under JMI environment is a hot issue at present. In this paper, the authors deeply discuss the question of the inventory time costs about the multi-produ...

To simplify complicated traditional cost estimation flow, this study emphasizes the cost estimation approach for plastic injection products and molds. It is expected designers and R&D specialists can consider the competitiveness of product cost in the early stage of product design to reduce product development time and cost resulting from repetitive modification. Therefore, the proposed cost es...

In neoclassical theory, product differentiation provides consumers with a variety of different products within a particular industry, rather than a homogeneous product that characterizes purely competitive markets. The welfare-enhancing benefit of product differentiation is the greater variety of products available to consumers, which comes at the cost of a higher average total cost of producti...